TAILIEUCHUNG - Exposure to ambient air pollution and prenatal and early childhood health effects

Health effects model. To estimate exposure to the PM10 produced by our sample plants, we use population data at the survey unit level—that is, at the level of areas geoestadísticas básicas (AGEBs) in Ciudad Juárez and census tracts in El Paso. We assign the inhabitants of each survey unit a distance-weighted average of PM10 concentrations predicted by the ISCST3 model at all model receptor points within 800 meters of the survey unit centroid. Next we estimate the health effects of this exposure using concentration-response (CR) coefficients reported in the epidemiological literature. CR coefficients indicate the expected. | European Journal of Epidemiology 2005 20 183-199 Springer 2005 DEVELOPMENTAL EPIDEMIOLOGY Exposure to ambient air pollution and prenatal and early childhood health effects Marina Lacasafia1 2 3 Ana Esplugues1 2 Ferran Ballester1 4 1 Epidemiology and Statistics Unit Valencian School of Studies for Health Valencia Spain 2 University Hospital La Fe Valencia Spain 3 Center for Environmental Health Center for Research in Populational Health National Institute of Public Health Cuernavaca Mexico 4Public Health Department History of Science and Gynaecology Miguel Hernandez University Alicante Spain Accepted in revised form 7 September 2004 Abstract. Over the last years concern for the possible influence of exposure to air pollutants in children during gestation or the first years of life has grown exposure levels which may be reached nowadays in our dwellings and in our streets. In the present study evidence over the possible impact of ambient air pollution on the foetus and the infants . less than 1 year published during the last decade 1994-2003 are revised. Studies on infant mortality and exposure to particles show an outstanding consistence in the magnitude of the effects despite the different designs used. As a whole data show that an increase in 10 g m3 of particle concentration measured as PM10 is associated with to about 5 increase in post-neonatal mortality for all causes and around 22 for post-neonatal mortality for respiratory diseases. Regarding damage in foetal health although results are not always consistent most studies show associations with exposure to air pollution during pregnancy. However the precise mechanisms of action of air pollutants on adverse reproductive results are still unknown so is the period of exposure most relevant during pregnancy and the specific pollutant which may represent a higher risk. Follow-up studies evaluating personal exposure to different air pollutants are required allowing for the adequate evaluation of the impact of .

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