TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 188

Pharmaceutical Substances Syntheses, Patents, Applications - Part 188. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Sevoflurane S 1871 1 -methyl-4-oxopiperidine- 5-carboxylate in Reference s DE2503 407 Akzo appl. NL-prior. . US 4 002 632 Akzo appl. NL-prior. . preparalion of ethyl 2-benzylphenyl acetate Kenyon . et al. J. Org. Chem. JOCEAH 28 3108 1963 . Yoshioka M. Osawa H. Fukuzawa s. Bull. Chem. Soc. Jpn. BCSJA8 55 3 877 1982 . Weizmann et al. J. Org. Chem. JOCEAH 15 918 920 926 1950 . McElvain Kent Stevens J. Am. Chem. Soc. JACSAT 68 1922 1946 . Meyer Ber. Dtsch. Chem. Ges. BDCGAS 21 1313 1888 . medical use for treatment of gastric ulcers US 4 447 437 Mochida appl. J-prior. . Formulation s tabl. 1 mg Trade Name s J Tecipul Mochida 1989 Sevoflurane ATC N01AB08 Use anesthetic inhalation RN 28523-86-6 MF C4H F7O MW LD 0 g kg M . 28300 ppm 3H M inhal. g kg R 28800 ppm 3H R inhal. CN l l l 3 3 3-hexafluoro-2- fluoromethoxy propane 1872 S Sibutramine hydrochloride h30 ỵcf3 cf3 1 1 1 3 3 3-hexo- f uoro-2-methoxy- propone CI Ck CF-j 1 1 1 3 3 3-hexa-fiuoro-2- chloro-methoxy propone I F xO .CF3 Sevoflurane BrFj or CIFj Sevoflurane Reference s a DE 1 954 268 Baxter appl. USA-prior. . US 3 683 092 Baxter appl. prior. . EP 341 005 BOC appl. USA-prior. . US 4 874 901 BOC appl. . b US 4 874 902 BOC appl. . alternative synthesis EP 42 412 Baxter Travenol appl. USA-prior. . Formulation s inhalation sol. 1 ml Trade Name s D Sevorane Abbott I Sevorane Abbott J Sevofrane Maruishi 1990 USA Sevorane Abbott Ultane Abbott Sibutramine hydrochloride ATC A08AA BTS-54524 Use antidepressant anorexic RN 125494-59-9 MF C17H26C1N HC1 H2O MW CN -1 - 4-chlorophenyl -A 7V-dimethyl-a- 2-methylpropyl cyclobutanemethanamine hydrochloride monohydrate -base RN 106650-56-0 MF C17H26C1N MW -anhydrous hydrochloride RN 84485-00-7 MF C17H26C1N HC1 MW -base RN .

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