TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 187

Pharmaceutical Substances Syntheses, Patents, Applications - Part 187. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Secobarbital S 1861 0 2-methyl- imidozole 1 2-methyl-5-nitroimidozole propylene oxide HCOOH -------- formic acid Secnidazole 0 . S K2C03 acetone ci 3 iVCH -N chlor - 2-methyl-1- ocetone imidazolyl - acetone 1. HNOj P2O5 2. NaBH4 CH3OH 2. sodium borohydride Secnidazole Reference s a Cosar C. et al. . ARZNAD 16 23 1966 . FR-M 3 270 Rhône-Poulenc appl. . FR 1 427 627 Rhône-Poulenc appl. . b DOS 2 107 423 Rhône-Poulenc appl. F-prior. . GB 1 278 758 Rhône-Poulenc valid from F-prior. . GB 1 265 466 Rhône-Poulenc valid from F-prior. . alternative syntheses DOS 2 107 405 Rhône-Poulenc appl. F-prior. . GB 1 278 757 Rhône-Poulenc valid from F-prior. . Formulation s tabl. 500 mg Trade Name s F Flagentyl Specia Rhône- Poulenc Secobarbital Quinalbarbitone ATC N05CA06 Use hypnotic RN 76-73-3 MF C12H SN2O3 MW EINECS 200-982-2 LD5o 145 mg kg M . 80 mg kg R . CN 5- 1 -methylbutyl -5- 2-propenyl -2 4 6 l 3 7 5 -pyrimidinetrione monosodium salt RN 309-43-3 MF C12H17N2NaO3 MW EINECS 206-218-4 LD5 110 mg kg M . 65 mg kg R . 125 mg kg R . 48 mg kg dog . 85 mg kg dog . 1862 S Secretin CH3 2-pentanol 2-pentyl bromide O CH O . NaOC2H5 ------------------- diethyl molonote ch3o diethyl 1 -methyl-butyl malonate I H2N O NqOC2H5 nh2 urea 5- 1 - methylbutyl - barbituric acid H C-VBr . KOH allyl bromide Referenced s LS 1 954 429 Eli Lilly 1934 CDN-prior. 1930 . Fonnulation s cps. 50 mg 100 mg powder 50 mg as sodium salt Trade Name s D Dormilfo Wachter -comb. F Binoctal Houdé -comb. wfm wfm Medinox Pfleger -comb. Dinoctin Spret- wfm Mauchant -comb. wfm Optipyrin Pfleger -comb. Divinoctal . -comb. wfm wfm Solamin Ardeypharm - Imménoctal Houdé wfm comb. wfm Imménoctal . wfm Tempidorm Roland - Insomnyl Elerté -comb. comb. wfm wfm Tempidorm N Roland - Noctadiol Millot-Solac - comb. wfm comb. wfm Trisomin Asche -comb. .

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