TAILIEUCHUNG - National Heart, Lung, and Blood Institute

The National Heart, Lung, and Blood Institute (or NHLBI) is a division of the National Institutes of Health, located in Bethesda, Maryland, USA. It is tasked with allocating about $ billion in tax revenue per year (fiscal year 2004 estimate) to advancing the understanding of the following issues: development and progression of disease, diagnosis of disease, treatment of disease, disease prevention, reduction of health care disparities within the American population, and advancing the effectiveness of the . medical system. NHLBI's current Director is Gary H. Gibbons, | Expert Panel Report 2 Guidelines for the Diagnosis and Management of Asthma NATIONAL institutes of health NATIONAL heart lung and blood institute Expert Panel Report 2 Clinical Practice Guidelines Guidelines for the Diagnosis and Management of Asthma NIH Publication No. 97-4051 July 1997 National Institutes OF Health National Heart Lung and Blood Institute CONTENTS Second Expert Panel on the Management of National Asthma Education and Prevention Program Coordinating National Asthma Education and Prevention Program Science Base METHODS USED TO DEVELOP THIS OVERVIEW OF THE Pathogenesis and Component 1 Measures of Assessment and Initial Assessment and Diagnosis of Periodic Assessment and Component 2 Control of Factors Contributing to Asthma Component 3 Pharmacologic Component 4 Education for a Partnership in Asthma Box 1. Major Events in the Development of PATHOGENESIS AND Key Differences From 1991 Expert Panel AIRWAY PATHOLOGY AND Child-Onset Adult-Onset RELATIONSHIP OF AIRWAY INFLAMMATION AND LUNG Airway Hyperresponsiveness .10 Airflow Obstruction .11 RELEVANCE OF CHRONIC AIRWAY INFLAMMATION TO ASTHMA Figure 1. Mechanisms Underlying the Definition of Asthma .8 Figure 2. Cellular Mechanisms Involved in Airway Inflammation .9 COMPONENT 1 MEASURES OF ASSESSMENT AND INITIAL ASSESSMENT AND DIAGNOSIS OF Key Points .15 Differences From 1991 Expert Panel Report .15 MEDICAL PHYSICAL PULMONARY FUNCTION TESTING SPIROMETRY .17 ADDITIONAL DIFFERENTIAL DIAGNOSIS OF GENERAL GUIDELINES FOR REFERRAL TO AN ASTHMA Box 1. Key Indicators for Considering a Diagnosis of Box 2. Importance of Spirometry in Asthma Diagnosis .20 .

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