TAILIEUCHUNG - báo cáo hóa học:" Change in condom and other barrier method use during and after an HIV prevention trial in Zimbabwe"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Change in condom and other barrier method use during and after an HIV prevention trial in Zimbabwe | van der Straten et al. Journal of the International AIDS Society 2010 13 39 http content 13 1 39 JOURNALOF THE INTERNATIONAL AIDS SOCIETY RESEARCH Open Access Change in condom and other barrier method use during and after an HIV prevention trial in Zimbabwe Ariane van der Straten1 2 Helen Cheng1 Alexandra M Minnis1 3 Abstract Background We examined the use of male condoms and the diaphragm following completion of a clinical trial of the diaphragm s HIV prevention effectiveness. In the trial called Methods for Improving Reproductive Health in Africa MIRA women were randomized to a diaphragm group diaphragm gel and condoms or a condom-only control group. At trial exit all women were offered the diaphragm and condoms. Methods Our sample consisted of 801 Zimbabwean MIRA participants who completed one post-trial visit median lapse nine months range two to 20 months . We assessed condom diaphragm and any barrier method use at last sex act at enrolment final MIRA and post-trial visits. We used multivariable random effects logistic regression to examine changes in method use between these three time points. Results and discussion In the condom group condom use decreased from 86 at the final trial visit to 67 post trial AOR 95 CI to . In the diaphragm group condom use was 61 at the final trial visit and did not decrease significantly post trial AOR 95 CI to while diaphragm use decreased from 79 to 50 post trial AOR 95 CI to . Condom use significantly decreased between the enrolment and post-trial visits in both groups. Use of any barrier method was similar in both groups it significantly decreased between the final trial and the post-trial visits but did not change between enrolment and the post-trial visits. Conclusions High condom use levels achieved during the trial were not sustained post trial in the condom group. Post-trial diaphragm use remained relatively high in the diaphragm group given its unknown .

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