TAILIEUCHUNG - Báo cáo y học: "Evaluation of maternal infusion therapy during pregnancy for fetal development"

Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Evaluation of maternal infusion therapy during pregnancy for fetal development. | Int. J. Med. Sci. 2005 2 137 Research paper International Journal of Medical Sciences ISSN 1449-1907 2005 2 4 137-142 2005 Ivyspring International Publisher. All rights reserved Evaluation of maternal infusion therapy during pregnancy for fetal development Dóra Petik Erzsébet Puhó and Andrew E. Czeizel Foundation for the Community Control of Hereditary Diseases Budapest Hungary Corresponding address Dr. Andrew E. Czeizel 1026 Budapest Torokvesz lejto 32. Hungary. e-mail czeizel@ Received Accepted Published The aim of this project was to study the possible association between maternal infusion treatments during pregnancy and variables offetal development as well as the occurrence of congenital abnormalities CA in a case-control design. The large population-based data set of the Hungarian Case-Control Surveillance of Congenital Abnormalities HCCSCA was evaluated based on the medically recorded infusion treatment during pregnancy. Of 22 843 case pregnant women who had newborns or fetuses with congenital abnormalities 112 while of 38 151 control pregnant women who had newborn infants without any defects 262 had infusion treatment during pregnancy. Infusion treatment was more frequent in the control group than in the case group with congenital abnormalities adjusted POR with 945 95 CI and there was no higher rate of maternal infusion treatments in any congenital abnormality group. Mean gestational age was shorter and mean birth weight was smaller in control newborn infants without CA born to mothers with infusion treatment during pregnancy than in the babies of mothers without infusion treatment. The prevalence of mild intrauterine growth retardation was more frequent in the fetuses of pregnant women with hyperemesis gravidarum treated with infusion. The results of the study suggest that infusion treatment of pregnant women did not associate with a higher risk of congenital abnormalities. In

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