TAILIEUCHUNG - Lecture Principles of biochemistry - Chapter 4 (part 1): Protein 3-Dimensional structure and function

In this chapter, you will: Define protein conformation and native conformation, know the difference between a simple and conjugated protein, know what homomeric and heteromeric proteins are, know what monomeric and multimeric proteins are, know the general properties of fibrous and globular proteins, know the 4 levels of protein structure, know the 4 non-covalent forces that are important in determining protein structure,. | Chapter 4 Protein 3-Dimensional Structure and Function Terminology Conformation – spatial arrangement of atoms in a protein Native conformation – conformation of functional protein Protein Classification Simple – composed only of amino acid residues Conjugated – contain prosthetic groups (metal ions, co-factors, lipids, carbohydrates) Example: Hemoglobin – Heme Protein Classification One polypeptide chain - monomeric protein More than one - multimeric protein Homomultimer - one kind of chain Heteromultimer - two or more different chains (. Hemoglobin is a heterotetramer. It has two alpha chains and two beta chains.) Protein Classification Fibrous – polypeptides arranged in long strands or sheets water insoluble (lots of hydrophobic AA’s) strong but flexible Structural (keratin, collagen) Globular – polypeptide chains folded into spherical or globular form water soluble contain several types of secondary structure diverse functions (enzymes, regulatory proteins) keratin collagen .

• Sinh học
• Principles of biochemistry
• Lecture Principles of biochemistry
• Biological systems
• Biochemical compounds
• Protein classification
• Protein 3 Dimensional structure
• Ebook Principles of biochemistry
• Principles of biochemistry (4th edition)
• The glyoxylate cycle
• Fatty acid catabolism
• Electron Transfer reactions
• Evolutionary foundations
• Protein interactions modulated
• Nucleic acid structure
• Biological macromolecules
• Chemical principles
• Properties of water
• Hydrogen bonding
• Amino acids
• Amino acid structure
• Protein purification
• Cell extract
• Protein folding
• Protein 3 D structure
• 3 D structure
• Oxygen binding curve
• Enzyme kinetics
• Rate constants
• Catalytic Power
• Classes of enzymes
• Inhibitor kinetics
• Enzyme regulation
• Allosteric regulation
• Enzyme action
• Mechanisms of enzyme action
• Ions Cofactors
• Metal ion
• Nguyên lý hóa sinh
• Biotin cofactor
• Conformation of monosaccharides
• Carbohydrate classifications
• Oligo carbohydrate
• Polysaccharides carbohydrate
• Lipid subclasses
• Acyl lipids
• Fluid mosaic model
• membrane transporters
• Metabolism proceed
• Anaeorbic process
• Triose Phosphate Isomerase
• Regulation of glycolysis
• Control points in glycolysis
• Citric acid cycle
• TCA cycle