TAILIEUCHUNG - Management of hepatitis C

Risk management is the process that allows IT managers to balance the operational and economic costs of protective measures and achieve gains in mission capability by protecting the IT systems and data that support their organizations’ missions. This process is not unique to the IT environment; indeed it pervades decision-making in all areas of our daily lives. Take the case of home security, for example. Many people decide to have home security systems installed and pay a monthly fee to a service provider to have these systems monitored for the better protection of their property. Presumably, the homeowners have weighed. | SI GN Scottish Intercollegiate Guidelines Network NHS Quality Improvement Scotland Management of hepatitis C 92 A national clinical guideline 1 Introduction 1 2 Testing 4 3 Prevention of secondary transmission 7 4 Referral 9 5 Children and hepatitis C 10 6 Acute hepatitis C 12 7 Assessment of liver disease 13 8 Progression of untreated disease 15 9 Treatment of chronic hepatitis C 18 10 Treatment of advanced infection 26 11 Nutrition supportive care and complementary therapies 28 12 Information for discussion with patients and carers 31 13 Implementation resource implications and audit 37 14 Development of the guideline 39 Abbreviations 43 References 44 December 2006 COPIES OF ALL SIGN GUIDELINES ARE AVAILABLE ONLINE AT KEY TO EVIDENCE STATEMENTS AND GRADES OF RECOMMENDATIONS LEVELS OF EVIDENCE 1 High quality meta-analyses systematic reviews of randomised controlled trials RCTs or RCTs with a very low risk of bias 1 Well conducted meta-analyses systematic reviews of RCTs or RCTs with a low risk of bias 1 - Meta-analyses systematic reviews of RCTs or RCTs with a high risk of bias 2 High quality systematic reviews of case control or cohort studies High quality case control or cohort studies with a very low risk of confounding or bias and a high probability that the relationship is causal 2 Well conducted case control or cohort studies with a low risk of confounding or bias and a moderate probability that the relationship is causal 2 - Case control or cohort studies with a high risk of confounding or bias and a significant risk that the relationship is not causal 3 Non-analytic studies eg case reports case series 4 Expert opinion GRADES OF RECOMMENDATION Note The grade of recommendation relates to the strength of the evidence on which the recommendation is based. It does not reflect the clinical importance of the recommendation. At least one meta-analysis systematic review of RCTs or RCT rated as 1 and directly applicable to the target population or A

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