TAILIEUCHUNG - Báo cáo y học: "Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized study. | Available online http content 10 2 R34 Research article Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis a randomized study Ann-Charlotte Elkan Beatrice Sjoberg Bjorn Kolsrud Bo Ringertz Ingiald Hafstrom and Johan Frostegard Rheumatology Unit Karolinska Institutet at Karolinska University Hospital Huddinge 141 86 Stockholm Sweden Corresponding author Johan Frostegard Received 15 Nov 2007 Revisions requested 11 Jan 2008 Revisions received 1 Feb 2008 Accepted 18 Mar 2008 Published 18 Mar 2008 Arthritis Research Therapy 2008 10 R34 doi ar2388 This article is online at http content 10 2 R34 2008 Elkan et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The purpose of this study was to investigate the effects of vegan diet in patients with rheumatoid arthritis RA on blood lipids oxidized low-density lipoprotein oxLDL and natural atheroprotective antibodies against phosphorylcholine antiPCs . Methods Sixty-six patients with active RA were randomly assigned to either a vegan diet free of gluten 38 patients or a well-balanced non-vegan diet 28 patients for 1 year. Thirty patients in the vegan group completed more than 3 months on the diet regimen. Blood lipids were analyzed by routine methods and oxLDL and anti-PCs were analyzed by enzyme-linked immunosorbent assay. Data and serum samples were obtained at baseline and after 3 and 12 months. Results Mean ages were years for the vegan group and years for controls. Gluten-free vegan diet induced lower body mass index BMI and .

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