TAILIEUCHUNG - Báo cáo y học: "Impact of concomitant aortic regurgitation on long-term outcome after surgical aortic valve replacement in patients with severe aortic stenosis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Impact of concomitant aortic regurgitation on long-term outcome after surgical aortic valve replacement in patients with severe aortic stenosis. | Catovic et al. Journal of Cardiothoracic Surgery 2011 6 51 http content 6 1 51 JCTS JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access Impact of concomitant aortic regurgitation on long-term outcome after surgical aortic valve replacement in patients with severe aortic stenosis Suad Catovic1 Zoran B Popovic2 Nebojsa Tasic3 Dusko Nezic3 Predrag Milojevic3 Bosko Djukanovic3 Sinisa Gradinac3 Lazar Angelkov3 and Petar Otasevic3 Abstract Background Prognostic value of concomitant aprtic regurgitation AR in patients operated for severe aortic stenosis AS is not clarified. The aim of this study was to prospectively examine the impact of presence and severity of concomitant AR in patients operated for severe AS on long-term functional capacity left ventricular LV function and mortality. Methods Study group consisted of 110 consecutive patients operated due to severe AS. The patients were divided into AS group 56 patients with AS without AR or with mild AR and AS AR group 54 patients with AS and moderate severe or very severe AR . Follow-up included clinical examination six minutes walk test 6MWT and echocardiography 12 and 104 months after AVR. Results Patients in AS group had lower LV volume indices throughout the study than patients in AS AR group. Patients in AS group did not have postoperative decrease in LV volume indices whereas patients in AS AR group experienced decrease in LV volume indices at 12 and 104 months. Unlike LV volume indices LV mass index was significantly lower in both groups after 12 and 104 months as compared to preoperative values. Mean LVEF remained unchanged in both groups throughout the study. NYHA class was improved in both groups at 12 months but at 104 months remained improved only in patients with AS. On the other hand distance covered during 6MWT was longer at 104 months as compared to 12 months only in AS AR group p 0 013 but patients in AS group walked longer at 12 months than patients in AS AR .

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