TAILIEUCHUNG - LIVER TRANSPLANTATION – TECHNICAL ISSUES AND COMPLICATIONS

However, despite sharing a common signature CLLs expressing mutated and unmutated IgVH genes differentially express more than 100 genes. Among these, over-expression of genes encoding zeta-chain-associated protein 70 (ZAP-70), lipoprotein lipase (LPL), BCL-7a, dystrophin and gravin are observed in the aggressive unmutated cases, while stable mutated cases over-express Wnt3, CTLA-4, NRIP1 nuclear receptor gene, ADAM29 and the transcription factor TCF7 [53]. These results suggest that indolent mutated and aggressive unmutated CLLs constitute two variants of the same disease. The reasons accounting for these striking differences in clinical outcomes of these two variants remain unsolved. . | LIVER TRANSPLANTATION - TECHNICAL ISSUES AND COMPLICATIONS Edited by Hesham Abdeldayem and Naglaa Allam Liver Transplantation - Technical Issues and Complications Edited by Hesham Abdeldayem and Naglaa Allam Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Romana Vukelic Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published February 2012 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Liver Transplantation - Technical Issues and Complications Edited by Hesham Abdeldayem and .

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