TAILIEUCHUNG - Prostate cancer - Diagnosis and treatment

For men with metastatic prostate cancer who are willing to accept the adverse impact on over- all survival and gynaecomastia in the hope of retaining sexual function, anti-androgen mono- therapy with bicalutamide (150 mg) 14 is appropriate. Healthcare professionals should begin androgen withdrawal and stop bicalutamide treatment in men with metastatic prostate cancer who are taking bicalutamide monotherapy and who do not maintain satisfactory sexual function. Intermittent androgen withdrawal may be offered to men with metastatic prostate cancer pro- viding they are informed that there is no long-term evidence of its effectiveness. . | NHS National Institute for Health and Clinical Excellence Issue date February 2008 Prostate cancer Diagnosis and treatment NICE clinical guideline 58 Developed by the National Collaborating Centre for Cancer NICE clinical guideline 58 Prostate cancer diagnosis and treatment Ordering information You can download the following documents from CG058 The NICE guideline this document - all the recommendations. A quick reference guide - a summary of the recommendations for healthcare professionals. Understanding NICE guidance - information for patients and carers. The full guideline - all the recommendations details of how they were developed and reviews of the evidence they were based on. For printed copies of the quick reference guide or Understanding NICE guidance phone NICE publications on 0845 003 7783 or email publications@ and quote N1457 quick reference guide N1458 Understanding NICE guidance . NICE clinical guidelines are recommendations about the treatment and care of people with specific diseases and conditions in the NHS in England and Wales This guidance represents the view of the Institute which was arrived at after careful consideration of the evidence available. Healthcare professionals are expected to take it fully into account when exercising their clinical judgement. The guidance does not however override the individual responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient in consultation with the patient and or guardian or carer and informed by the summary of product characteristics of any drugs they are considering. National Institute for Health and Clinical Excellence MidCity Place 71 High Holborn London WC1V 6NA National Institute for Health and Clinical Excellence 2008. All rights reserved. This material may be freely reproduced for educational and not-for-profit purposes. No reproduction by or for commercial organisations or for commercial

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