TAILIEUCHUNG - Phenolic compounds from Trigonostemon honbaensis and their cytotoxic activity
Seven phenolic compounds including (±)-erythro-1-(3 ,4 ,5 -trimethoxyphenyl)propane-1,2-diol (1), (±)-threo-1- (3 ,4 ,5 -trimethoxyphenyl)propane-1,2-diol (2), (R)-3-3-(3 ,4 -dimethoxyphenyl)propane-1,2-diol (3), (±)-3-(3 ,4 ,5 - trimethoxyphenyl)propane-1,2-diol (4), (+)-syringaresinol (5), (7S,8R,8′R)-5,5′-dimethoxylariciresinol (6), juniperoside (7) were isolated from the leaves of Trigonostemon honbaensis. Their chemical structures were determined using ESIMS, 1D NMR, and 2D NMR spectra and in comparison with the reported literature. Compounds1- 7 were reported from Trigonostemongenus for the first time. At concentration of 30 µM, compounds 1-7 exhibited weak cytotoxic activity with cell viability percentages as low as ± % and ± % on CAL-27 and MDA-MB231 cell lines, respectively. |
đang nạp các trang xem trước
