TAILIEUCHUNG - Arachidonic acid: Physiological roles and potential health benefits – A review

It is time to shift the arachidonic acid (ARA) paradigm from a harm-generating molecule to its status of polyunsaturated fatty acid essential for normal health. ARA is an integral constituent of biological cell membrane, conferring it with fluidity and flexibility, so necessary for the function of all cells, especially in nervous system, skeletal muscle, and immune system. Arachidonic acid is obtained from food or by desaturation and chain elongation of the plant-rich essential fatty acid, linoleic acid. Free ARA modulates the function of ion channels, several receptors and enzymes, via activation as well as inhibition. That explains its fundamental role in the proper function of the brain and muscles and its protective potential against Schistosoma mansoni and S. haematobium infection and tumor initiation, development, and metastasis. Arachidonic acid in cell membranes undergoes reacylation/deacylation `, which keep the concentration of free ARA in cells at a very low level and limit ARA availability to oxidation. Metabolites derived from ARA oxidation do not initiate but contribute to inflammation and most importantly lead to the generation of mediators responsible for resolving inflammation and wound healing. Endocannabinoids are oxidation-independent ARA derivatives, critically important for brain reward signaling, motivational processes, emotion, stress responses, pain, and energy balance. | Arachidonic acid: Physiological roles and potential health benefits – A review

• Y khoa - Dược
• Arachidonic acid
• Ion channels
• Physiological roles
• Potential health benefits
• Membranes undergoes reacylation cycles
• Delta desaturases
• Lipo and cyclo oxygenases
• Synopsis of arachidonic acid metabolism
• Arachidonic acid metabolism
• Is arachidonic acid
• Arachidonic acid an endoschistosomicide
• Rat schistosomiasis
• Oil Red O staining
• Specific anti ARA antibody based
• Polyunsaturated fatty acids
• Sulfur amino acid
• Hydrogen sulfide
• Nitric oxide
• Metabolic engineering
• Potential source
• Plants as potential source
• BMC Biotechnology
• Mortierella Alpina
• Dissolved oxygen
• Heavy ion mutagenesis
• Octyl gallate
• Molecular breeding
• Fatty acid desaturase
• Mortierella alpina 1S 4
• Unsaturated fatty acids
• Free radicals
• Metabolites function
• Endogenous antimicrobial molecules
• Lipoxin A4
• Pre eclampsia
• Diabetes mellitus
• Hypertension and diabetes mellitus
• BMC Cancer
• Cancer remains
• Prostaglandin E2
• Methodological limitations
• Type 2 cytokines
• Schistosomiasis vaccine
• Metabolic syndrome
• Pathogenic potential of uric acid
• BMC Geriatrics
• Lifestyle habits
• Long chain polyunsaturated fatty acids
• Cognitive leisure activities
• Maintaining cognitive function
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• báo cáo hóa học
• công trình nghiên cứu về hóa học
• tài liệu về hóa học
• cách trình bày báo cáo
• Report medicine
• traditional medicine
• scientific reports
• medical knowledge
• medical research
• analysis of cytoplasmic
• Structural biochemistry
• oxidation
• bacteria
• chemical reaction
• Leptinotarsa decemlineata
• Treating fungus injected
• Eicosanoid biosynthesis
• B
• bassiana
• L
• decmlineata
• Schistosoma mansoni
• Antibody response
• Uric and arachidonic acid
• Papain enzymatic activity
• The protection induced
• Cysteine protease against
• Schistosoma haematobium
• Excretory–secretory products
• Type 2 adjuvants
• BMC Chemistry
• Dibenzylidene ketone derivatives
• Computational studies
• Human capsaicin receptor
• Journal of Chemistry
• Nitro compounds
• N carbamothioyl
• Soybean 15 LOX
• Nitrophenoxy chromenone derivative
• Arachidonic acid (AA)
• BMC Pediatrics
• Human milk provides
• Infant nutrition
• Multifunctional iron binding protein
• Adjusted arachidonic acid
• BMC Plant Biology
• Diacylglycerol acyltransferase
• Lipid droplet
• Lobosphaera incisa
• Genome Biology
• Ovarian carcinoma
• Tumor associated macrophages
• Tumor microenvironment
• Malignancy associated ascites
• Signaling network