TAILIEUCHUNG - Deeper insight into maternal genetic assessments and demographic history for Egyptian indigenous chicken populations using mtDNA analysis

This study principally sought to reveal the demographic expansion of Egyptian indigenous chickens (EIC) using representative breeds: Sinai (North), Fayoumi (Middle) and Dandarawi (South) of Egypt as well as to deeply clarify their genetic diversity, possible matrilineal origin and dispersal routes. A total of 33 partial mitochondrial DNA sequences were generated from EIC and compared with a worldwide reference dataset of 1290 wild and domestic chicken sequences. Study populations had 12 polymorphic variable sites and 7 haplotypes. A lack of maternal substructure between EIC was detected (FST = ). The unimodal mismatch distribution and negative values of Tajima’s D ( ) and Fu’s Fs ( ) indicated demographic expansion among EIC and pointed to Fayoumi as the oldest EIC population. Egyptian haplotypes were clustered phylogenetically into two divergent clades. Their phylogeography revealed an ancient single maternal lineage of Egyptian chickens likely derived from IndianSubcontinent. Moreover, a recent maternal commercial heritage possibly originated in Yunnan-Province and/or surrounding areas was admixed restrictedly into Sinai. | Deeper insight into maternal genetic assessments and demographic history for Egyptian indigenous chicken populations using mtDNA analysis

• Sinh học
• Mitochondrial DNA
• Maternal lineages
• Egyptian indigenous chicken
• Demographic history
• mtDNA analysis
• BMC Cancer
• Mitochondrial DNA repair
• Mitochondrial DNA mutation
• Accumulation of mitochondrial DNA
• Including cancer
• Oxidative phosphorylation
• Mitochondrial DNA disorders
• Mitochondrial DNA mutations
• Calcium homeostasis
• Green tea extract
• DNA damage
• Induced hepatic mitochondrial DNA
• Albino wistar rats
• BMC Pediatrics
• Multiorgan failure
• Plasma mitochondrial DNA
• Determining disease severit
• BMC Molecular and Cell Biology
• Thymidine kinase 2
• Thymidylate synthase
• Mitochondrial DNA depletion
• Ribonucleotide reductase
• BMC Musculoskeletal Disorders
• Adolescent idiopathic scoliosis
• Circulating cell free nuclear DNA
• Circulating cell free mitochondrial DNA
• Sex differences
• Lenke types
• BMC Pharmacology and Toxicology
• Caenorhabditis elegans
• Mitochondrial DNA damage
• Mitochondrial dysfunction
• Ultraviolet C radiation
• Early life exposure
• BMC Genomics
• Substitution models
• Neighboring nucleotides
• Global human mitochondrial DNA
• BMC Pulmonary Medicine
• Oxidative stress
• Real Time PCR
• Unmethylated DNA molecule
• Nanopore sequencing
• MinION device
• Single nucleotide polymorphism
• Mitochondrial genomes
• Genome Biology
• Long reads
• Mitochondrial genome
• Mitochondrial structure
• BMC Genetics
• SNP array
• Haplogroup assignment
• Mitochondrial haplogroup assignment
• Distribution and phylogenetic
• DNA extraction
• Relationships of snappers
• Phylogenetic relationships of snappers
• DNA sequence variation of the mitochondrial
• Mitochondrial DNA content
• Peripheral blood leukocyte
• Glioma risk
• Colorectal cancer
• Copy number
• Quantitative PCR
• BMC Bioinformatics
• K mer
• Next generation sequencing
• De novo assembly
• Healthy aging
• Whole genome
• Human nuclear genome
• Non bioinformaticians
• Missense mutation
• Protein multiple sequence alignment
• Screening proposal
• Plasma mtDNA level
• Acute lung injury
• Mitochondria regulate innate immunity
• Athletic performance
• Sprint athletes
• MtDNA copy number
• Whole genome sequencing
• TwinsUK cohorts
• Horizontal gene transfer
• Nuclear mitochondrial DNA
• Nuclear plastid DNA
• Non homologous end joining
• Bdelloid rotifers
• Gastric cancer
• Mitochondrial NADH dehydrogenase subunit 3
• Reactive oxygen species
• Human mitochondrial mutations
• Chromatin immunoprecipitation sequencing
• ChIP seq experiments
• Gene rearrangement
• Duplicate control regions