TAILIEUCHUNG - Study clinical, paralcinical features and expression of VEGF gene in serum of patients with non small cell lung cancer

Objectives: To investigate clinical, subclinical features and expression of VEGF gene in nonsmall cell lung cancer in order to accurately diagnose the disease at an earlier stage, before the disease has developed, which can lead to a worse prognosis. Subjects and methods: One hundred patients with non-small cell lung cancer and 51 healthy subjects participated in an analytical cross-sectional study with comparison group. | Journal of military pharmaco-medicine n09-2018 STUDY CLINICAL, PARALCINICAL FEATURES AND EXPRESSION OF VEGF GENE IN SERUM OF PATIENTS WITH NON-SMALL CELL LUNG CANCER Ho Van Son1,2; Ngo Tat Trung3; Nguyen Linh Toan1 SUMMARY Objectives: To investigate clinical, subclinical features and expression of VEGF gene in nonsmall cell lung cancer in order to accurately diagnose the disease at an earlier stage, before the disease has developed, which can lead to a worse prognosis. Subjects and methods: One hundred patients with non-small cell lung cancer and 51 healthy subjects participated in an analytical cross-sectional study with comparison group. Results: The relative expression mRNA of the VEGF gene in the study group was significantly higher compared with the control group (p ). 4. The diagnostic value of lung cancer of serum mRNA VEGF expression. Analysis of the diagnostic value of serum mRNA VEGF expression for lung cancer, we analyzed the area under the mRNA VEGF expression curve between lung cancer patients and healthy people (figure 2). Figure 2: The area under the AUC curve expressing of serum mRNA VEGF. The mRNA VEGF expression level in serum was capable of distinguishing patients with lung cancer and healthy people by the area under the AUC curve reached (sensitivity , specificity , p = ). 104 Journal of military pharmaco-medicine n09-2018 DISCUSSION Primary lung cancer is one of the most common types of malignancy and is the leading cause of death in cancer. Our research showed that the mRNA expression of VEGF gene in the serum of lung cancer patients was significantly higher than that of healthy individuals. This suggested that determining the level of VEGF gene expression in plasma may be one of the potential non-invasive methods for the screening of lung cancer. Of all the vascular factors involved the process of vessel formation related to tumor, VEGF is known to be one of the most important factors in normal physiological and .

• Y khoa - Dược
• Lung cancer
• Non small cell lung cancer
• Expression of VEGF gen
• Paraclinical features
• Analytical cross sectional
• BMC Cancer
• Quantitative real time PCR
• Lung squamous carcinoma
• Cancer stem cells
• Oct4 overexpressing lung cancer
• Human lung cancer xenograft model
• Disease free survivals
• Lung Cancer Screening
• Racial disparities
• Cancer Screening
• Lung Cancer diagnosis
• Screening adherence
• BMC Pulmonary Medicine
• Lung nodule
• Incidental lung nodule
• Interventional pulmonology
• Value of PET CT
• Lymph node in small cell lung cancer
• Organization classification of lung tumours
• Non small cell lung carcinoma
• mRNA expression
• Primary lung cancer
• Diagnostic role of Ciz1b
• Lung cancer patients
• Lung cancer risk
• Low dose helical CT screening
• Lung cancer risk test biomarker
• Genome maintenance
• Primary synchronous lung cancer
• Metastatic lung cancer
• Microsatellite analysis
• Tumor lineage
• Lymphocyte ratio
• Advanced lung cancer inflammation index
• Systemic inflammation
• Early stage lung cancer
• Diagnostic tests
• Genetic association
• Chinese population
• Overall lung cancer
• Including lung cancer
• Immune checkpoint inhibitor
• Small cell lung cancer
• Lung inflammation
• Metabolic phenotype
• Pulmonary imaging
• Interstitial lung disease
• Drug induced interstitial lung disease
• Anticancer therapy
• Stereotactic radiotherapy
• Metastatic lung tumor
• Prognostic factor
• Lung development
• Lung adenocarcinoma
• Overall survival
• EGFR mutation
• Family history of cancer
• Inherited susceptibility
• Cancer predisposition genes
• Lung cancer aetiology
• Deleted in liver cancer 1
• Cancer related mortality
• Radiation therapy
• ABC of lung cancer
• Malignant pleural mesothelioma
• Service organization
• Performance analysis of lung cancer diagnosis algorithms on X Ray images
• Lung cancer diagnosis algorithms on X Ray images
• X Ray images
• Characterize lung cancer
• K Nearest Neighbor
• Distal metastases
• Therapeutic potential
• Human lung cancer
• SK MES 1 lung carcinoma cell growth
• Health inequalities
• Carbon monoxide
• Lung health check
• Multivariate regression analysis
• Multiple myeloma
• Occult lung cancer
• Non small cell lung cancer
• Tumor lymph node metastasis
• Stage I IIIA
• Surgical outcome
• Pulmonary disease
• Patients with lung cancer
• C T1N0M0 primary lung cancer