TAILIEUCHUNG - Phenyl derivatives from the leaves of the vietnamese plant antidesma hainanensis
Their chemical structures were determined using 1D, 2D-NMR and ESI-MS analysis as well as by comparison with reported data. This is the first report of these compounds from A. hainanensis. | Journal of Science and Technology 55 (1) (2017) 8-14 DOI: PHENYL DERIVATIVES FROM THE LEAVES OF THE VIETNAMESE PLANT ANTIDESMA HAINANENSIS Le Canh Viet Cuong1, Bui Huu Tai1, Nguyen Xuan Nhiem1, Pham Hai Yen1, Hoang Le Tuan Anh1, Le Mai Huong2, Phan Van Kiem1, * 1 2 Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi Institute of Natural Products Chemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi * Email: phankiem@ Received: 15 July 2016; Accepted for publication: 26 November 2016 ABSTRACT Five phenyl derivatives 1-O-(2′,4′ -dihydroxy-6’-methoxyphenyl)-6-O-(4′′-hydroxy-3′′,5′′dimethoxybenzoyl)-β-D-glucopyranoside (1), 4′-O-[6′′-O-(4′′′-hydroxy-3′′′,5′′′-imethoxybenzoyl) -β-D-glucopyranosyl]-3′-hydroxyphenethyl alcohol (2), 4-hydroxymethyl-2-methoxyphenyl-6′O-syringoyl-β-D-glucopyranoside (3), phenethyl-6-O-α-L-arabinofuranosyl-β-D-glucopyranoside (4), and 1-O-syringoyl-β-D-glucopyranoside (5) were isolated from the methanol extract of the leaves of the Vietnamese plant Antidesma hainanensis. Their chemical structures were determined using 1D, 2D-NMR and ESI-MS analysis as well as by comparison with reported data. This is the first report of these compounds from A. hainanensis. Keywords: Antidesma hainanensis, Euphorbiaceae, phenyl derivative. 1. INTRODUCTION Antidesma is a genus of tropical plants belonging to Euphorbiaceae family and comprises about 100 species in the world, 29 species in Vietnam [1]. The study of the chemical composition showed that this genus contains alkaloids, coumarinolignans, megastigmanes, lignan glucosides, benzopyranones, ferulic acids, and particularly polyphenols, in addition to oil [2]. Biological activities of this genus have been studied, such as antifungal, cytotoxic, and antioxidant activities [3]. However, chemical composition and biological activity of A. hainanensis have not been extensively reported up to now. This paper reports the isolation and structure .
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