TAILIEUCHUNG - Management of early rheumatoid arthritis

The threat statement, or the list of potential threat-sources, should be tailored to the individual organization and its processing environment (., end-user computing habits). In general, information on natural threats (., floods, earthquakes, storms) should be readily available. Known threats have been identified by many government and private sector organizations. Intrusion detection tools also are becoming more prevalent, and government and industry organizations continually collect data on security events, thereby improving the ability to realistically assess threats | i SIGNI. Scottish Intercollegiate Guidelines Network Part of NHS Quality Improvement Scotland NHS Quality Improvement Scotland Management of early rheumatoid arthritis 123 A national clinical guideline February 2011 KEY TO EVIDENCE STATEMENTS AND GRADES OF RECOMMENDATIONS LEVELS OF EVIDENCE 1 High quality meta-analyses systematic reviews of RCTs or RCTs with a very low risk of bias 1 Well conducted meta-analyses systematic reviews or RCTs with a low risk of bias 1- Meta-analyses systematic reviews or RCTs with a high risk of bias 2 High quality systematic reviews of case control or cohort studies High quality case control or cohort studies with a very low risk of confounding or bias and a high probability that the relationship is causal 2 Well conducted case control or cohort studies with a low risk of confounding or bias and a moderate probability that the relationship is causal 2 - Case control or cohort studies with a high risk of confounding or bias and a significant risk that the relationship is not causal 3 Non-analytic studies eg case reports case series 4 Expert opinion GRADES OF RECOMMENDATION Note The grade of recommendation relates to the strength of the evidence on which the recommendation is based. It does not reflect the clinical importance of the recommendation. A At least one meta-analysis systematic review or RCT rated as 1 and directly applicable to the target population or A body of evidence consisting principally of studies rated as 1 directly applicable to the target population and demonstrating overall consistency of results B A body of evidence including studies rated as 2 directly applicable to the target population and demonstrating overall consistency of results or Extrapolated evidence from studies rated as 1 or 1 C A body of evidence including studies rated as 2 directly applicable to the target population and demonstrating overall consistency of results or Extrapolated evidence from studies rated as 2 D Evidence level 3 or 4 or .

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