TAILIEUCHUNG - Ebook The developing human clinically oriented embryology (10th edition): Part 2

(BQ) Part 2 book "The developing human clinically oriented embryology" presents the following contents: Alimentary system, urogenital system, cardiovascular system, skeletal system, muscular system, nervous system, development of eyes and ears, integumentary system, human birth defects,. | Alimentary System Foregut 210 Development of Esophagus 210 Development of Stomach 211 Omental Bursa 211 Development of Duodenum 214 Development of Liver and Biliary Apparatus 217 Development of Pancreas 219 Development of Spleen 221 Midgut 221 Herniation of Midgut Loop 223 Rotation of Midgut Loop 224 Retraction of Intestinal Loops 224 Cecum and Appendix 225 Hindgut 233 Cloaca 233 Anal Canal 233 Summary of Alimentary System 234 Clinically Oriented Problems 239 T he alimentary system digestive system is the digestive tract from the mouth to the anus with all its associated glands and organs. The primordial gut forms during the fourth week as the head caudal eminence tail and lateral folds incorporate the dorsal part of the umbilical vesicle yolk sac see Chapter 5 Fig. 5-1 . The primordial gut is initially closed at its cranial end by the oropharyngeal membrane see Chapter 9 Fig. 9-1E and at its caudal end by the cloacal membrane Fig. 11-1B . The endoderm of the primordial gut forms most of the gut epithelium and glands. Mesenchymal factors FoxF proteins control proliferation of the endodermal epithelium that secretes sonic hedgehog Shh . The epithelium of the cranial and caudal ends of the alimentary tract is derived from ectoderm of the stomodeum and anal pit proctodeum see Fig. 11-1A and B . Fibroblast growth factors FGFs are involved in early anteroposterior axial patterning and it appears that FGF-4 signals from the adjacent ectoderm and mesoderm induce the endoderm. Other secreted factors such as activins members of the transforming growth factor- superfamily contribute to the formation of the endoderm. The endoderm specifies temporal and positional information which is essential for the development of the gut. The muscular connective tissue and other layers of the wall of the alimentary tract are derived from the splanchnic mesenchyme surrounding the primordial gut. For descriptive purposes the primordial gut is divided into three parts foregut midgut and .

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