TAILIEUCHUNG - Radiological Findings of Extensively Drug-Resistant Pulmonary Tuberculosis in Non-AIDS Adults: Comparisons with Findings of Multidrug-Resistant and Drug-Sensitive Tuberculosis

This study was designed to describe the radiological findings of extensively drug-resistant (XDR) pulmonary tuberculosis (TB) and to compare the observed findings with findings of drug-sensitive (DS) and non-XDR multidrug- resistant (MDR) TB in non-AIDS patients. Materials and Methods: From September 1994 to December 2007, 53 MDR TB patients (M:F = 32:21; mean age, 38 years) and 15 XDR TB non-AIDS patients (M:F = 8:7; mean age, 36 years) were enrolled in the study. All of the MDR TB patients had received no treatment or less than one month of anti-TB treatment. In addition, all XDR TB patients received either no anti-TB treatment or only first-line anti-TB drugs. In. | Radiological Findings of Extensively Drug-Resistant Pulmonary Tuberculosis in Non-AIDS Adults Comparisons with Findings of Multidrug-Resistant and Drug-Sensitive Tuberculosis Jihoon Cha MD1 Ho Yun Lee MD1 Kyung Soo Lee MD1 Won-Jung Koh MD2 O Jung Kwon MD2 Chin A Yi MD1 Tae Sung Kim MD1 Myung Jin Chung MD1 Index terms Computed tomography CT high-resolution Lung infection Tuberculosis pulmonary Thorax radiography DOI Korean J Radiol 2009 10 207-216 Received October 29 2008 accepted after revision February 4 2009. Department of Radiology and Center for Imaging Science 2Division of Pulmonary and Critical Care Medicine Department of Internal Medicine Samsung Medical Center Sungkyunkwan University School of Medicine Seoul 135-710 Korea This study was presented as a scientific poster at the 2008 RSNA scientific assembly Paper number LL-CH-D03 . The SRC ERC Program of MOST KOSEF R11-2002-103 supported this study. Address reprint requests to Kyung Soo Lee MD Department of Radiology and Center for Imaging Science Samsung Medical Center Sungkyunkwan University School of Medicine 50 Ilwon-dong Gangnam-gu Seoul 135-710 Korea. Tel. 822 3410-2511 Fax. 822 3410-2559 e-mail Objective This study was designed to describe the radiological findings of extensively drug-resistant XDR pulmonary tuberculosis TB and to compare the observed findings with findings of drug-sensitive DS and non-XDR multidrug-resistant MDR TB in non-AIDS patients. Materials and Methods From September 1994 to December 2007 53 MDR TB patients M F 32 21 mean age 38 years and 15 XDR TB non-AIDS patients M F 8 7 mean age 36 years were enrolled in the study. All of the MDR TB patients had received no treatment or less than one month of anti-TB treatment. In addition all XDR TB patients received either no anti-TB treatment or only first-line anti-TB drugs. In addition 141 consecutive DS TB patients M F 79 62 mean age 51 years were also enrolled in the study for .

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