TAILIEUCHUNG - Air pollution and allergens

Further study is needed to disentangle this interaction and the underlying mechanisms. moreover, the balance of evidence maintains that outdoor air pollution has a mod- est effect on the occurrence of anemia in schoolchildren. Exposure to air pollution may increase the risk of anemia in children through several mechanisms The biological mechanisms by which air pollutants may interfere with the process of red blood cell production are reflected in the synthesis of hem, the forming of red blood cells, and its life-expectancy. Toxic materials from the air lead to significant damage of red blood cells such as reduced he- moglobin concentrations, the. | Air pollution and allergens I R Art TA 1 I Ml illnl 2 A dpi Cl ivilln 3 I RávĩIa 4 M Fprrpr5 I Iái irpm II 6 uiioi euvo Vila eiiei uicuui J Montoro 7 J Sastre 8 A Valero1 1 Allergy Unit. Service of Pneumology and Respiratory Allergy Hospital Clinic ICT Barcelona Spain 2 Rhinology Unit ENT Service ICEMEQ Hospital Clinic Barcelona Spain 3 Clinica Dr. Lobatón Cadiz Spain 4 Service of Immunoallergy Hospital Clinico Salamanca Spain 5 Department of Allergology Clinica Universitaria de Navarra Pamplona Spain 6 Service of Allergy Hospital de Basurto Bilbao Spain 7 Allergy Unit Hospital La Plana Villarreal Castellón Spain 8 Service of Allergy Fundación Jimenez Diaz Madrid Spain Summary It is well known that the prevalence of allergic diseases has increased in recent decades in the industrialized world. Exposure to environmental pollutants may partially account for this increased prevalence. In effect air pollution is a growing public health problem. In Europe the main source of air pollution due to particles in suspension is represented by motor vehicles - particularly those that use diesel fuel. Diesel exhaust particles DEPs are composed of a carbon core upon which high-molecular weight organic chemical components and heavy metals deposit. Over 80 of all DePs are in the ultrafine particle range pm in diameter . Air pollutants not only have a direct or indirect effect upon the individual but also exert important actions upon aeroallergens. Pollen in heavily polluted zones can express a larger amount of proteins described as being allergenic. Through physical contact with the pollen particles DEPs can disrupt the former leading to the release of paucimicronic particles and transporting them by air - thus facilitating their penetration of the human airways. Climate change in part gives rise to variations in the temperature pattern characterizing the different seasons of the year. Thus plants may vary their pollination calendar advancing and prolonging their .

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