TAILIEUCHUNG - Báo cáo sinh học: " Persistence of accuracy of genomic estimated breeding values over generations in layer chickens"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Persistence of accuracy of genomic estimated breeding values over generations in layer chickens | Wolc et al. Genetics Selection Evolution 2011 43 23 http content 43 1 23 GSE Ge n et i cs Selection Evolution RESEARCH Open Access Persistence of accuracy of genomic estimated breeding values over generations in layer chickens Atim lr 1 2loci IC Ạ rTỉnnr t3 Pofolz Qoi f 2r3 l nof p Pl iltTM 3 Moil p CYQi li lix Tỉn3 Pl iH Mf Proicinrior4 I IsỉHior2 Annd wolc Jesus Aidngo Petek settdi Jdnet E Fulton Neil P Osullivdn Rudoli Pieisingei Ddvid Hdbiei Rohan Femdndo2 Doiidn J Gdiiick2 dnd Jdck CM Dekkeis2 Abstract Background The predictive dbility of genomic estimdted breeding vdlues GEBV oiigindtes both fiom dssocidtions between high-density mdtkets dnd QTL Qudntitdtive Trait Loci dnd fiom pedigree infotmdtion. Thus GEBV die expected to provide moie peisistent dccuidcy ovei successive generations thdn breeding vdlues estimdted using pedigiee-bdsed methods. The objective of this study wds to evdludte the dccuidcy of GEBV in d closed populdtion of ldyei chickens dnd to qudntify theii peisistence ovei five successive generations using mdikei oi pedigree infoimdtion. Methods The training ddtd consisted of 16 tidits dnd 777 genotyped dnimdls fiom two generations of d biown-egg ldyei breeding line 295 of which hdd individudl phenotype iecoids while otheis hdd phenotypes on 2 738 non-genotyped ieldtives oi simildi ddtd dccumuldted ovei up to five generations. Vdliddtion ddtd included phenotyped dnd genotyped biids fiom five subsequent generations on dveidge 306 biids geneidtion . Biids weie genotyped foi 23 356 segiegdting SNP. Animdl models using genomic oi pedigree ieldtionship mdtiices dnd Bdyesidn model dveidging methods weie used foi training dndlyses. Accuracy wds evdludted ds the coiieldtion between EBV dnd phenotype in vdliddtion divided by the squdie ioot oftidit heiitdbility. Results Pedigree ieldtionships in outbied populdtions die reduced by 50 dt edch meiosis therefore dccuidcy is expected to deciedse by the squdie ioot of eveiy geneidtion ds

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