TAILIEUCHUNG - Báo cáo y học: "Long-term outcome in medical patients aged 80 or over following admission to an intensive care unit"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Long-term outcome in medical patients aged 80 or over following admission to an intensive care unit. | Roch et al. Critical Care 2011 15 R36 http content 15 1 R36 KS CRITICAL CARE RESEARCH Open Access Long-term outcome in medical patients aged 80 or over following admission to an intensive care unit 1 1 2 1 1 1 Antoine Roch Sandrine Wiramus Vanessa Pauly Jean-Marie Forel Christophe Guervilly Marc Gainnier Laurent Papazian 1 Abstract Introduction The aim of this study was to evaluate factors influencing short- and long-term survival in medical patients aged 80 and over following admission to an intensive care unit. Methods All patients aged 80 years or over and admitted between 2001 and 2006 were included in this study. Survival was evaluated between the time of admission and June 2009 factors associated with mortality were determined. Health-related quality of life was evaluated using Short Form SF -36 in long-term survivors. Results For the 299 patients included mean age 84 4 y hospital mortality was 55 . Factors independently associated with hospital mortality were a higher SAPS II score at ICU admission the existence of a fatal disease as reflected by the McCabe score and a cardiac diagnosis at admission. In the 133 hospital survivors median survival time was 710 days 95 CI 499-921 . Two-year mortality rates were 79 of the initial cohort and 53 of hospital survivors. The standardized ratio of mortality at 2 years after hospital discharge was 95 CI when compared with age- and gender-adjusted mortality of the general population. Factors independently associated with mortality at 2 years after hospital discharge were SAPS II score at ICU admission and the McCabe score. Conversely functional status prior to admission as assessed by Knaus or Karnofsky scores was not associated with long-term mortality. In long-term survivors SF-36 physical function scores were poor but scores for pain emotional well-being and social function were not much affected. Conclusions The severity of acute disease at admission influences mortality at the hospital .

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