TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 32

Pharmaceutical Substances Syntheses, Patents, Applications - Part 32. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Butylscopolammonium bromide B 311 Butylscopolammonium bromide atc aosbboi Butylscopolamine bromide Scopolamine butyl bromide se antispasmodic Hyoscin butyl bromide RN 149-64-4 MF C21H30BrNO4 MW EINECS 205-744-1 LD50 mg kg M . 1170 mg kg M . 24 mg kg R . 1040 mg kg R . CN 7 5 - la 2ß 4ß 5a 7ß -9-butyl-7- 3-hydroxy- 1-oxo-2-phenylpropoxy -9-methyl-3-oxa-9-azoniatricyclo 02 4 nonane bromide CH3CN butyl bromide -scopolamine Reference s DE 856 890 Boehringer Ing. appl. 1950 . Formulation s amp. 20 mg ml drg. 10 mg f. c. tabl. 10 mg suppos. mg 10 mg labl. 20 mg vial 200 mg 10 ml Trade Name s D Buscopan Boehringer Buscopan Boehringer- Hyospan Toiyo Ing. -comb. Tanabe Moryspan Beppu F Genoscopolamine Amino Buscoridin Kanebo Reladan Isei Scopoderm Novartis Buscote Kotani Scobro Ono GB Buscopan Boehringer Ing. Buspon Toyo Pharmar Scobron Mohan I Buscopan Boehringer Ing. Butibol Towa Scobutylamin Horii Buscopan composto Butylpan Hokuriku Scordin-B Ono Boehringer Ing. -comb. Butymide Ohta Scorpan Kanto Tranquo-Buscopan Butysco Kobayashi Sparicon Yamanouchi Boehringer Ing . -comb. Diaste-M Fukuchi- Spasmopan Nichiiko J Antispasmin Green Cross Fujizoki Stibron Iwaki Bubusco-S Sawai Hyoscomin Vitacain 312 C Cabergoline Cabergoline ATC G02CB03 Use dopamine D2 receptor antagonist prolactin inhibitor for prevention or suppression of puerperal lactation RN 81409-90-7 MF C26H37N5O2 MW CN 8P -A- 3- Dimethylamino propyl -A - ethylamino carbonyl -6- 2-propenyl ergoline-8-carboxamide 8 -methoxycarbonyl- ergoline cf. pergolide synthesis Br - CH2 1. K2COj dmf 2. NaOH CH3OH COOH 6-allyl-8 3-ergoline-carboxylic acid I allyl bromide N-ethyl-N - 3- dimethyl-amino propyl corbo-diimide H C J -N C N- H C ch CH- 3-dimethylamino- propylamine diisopropylcarbodiimide 6-allyl-N- 3- dimethyl- amino propyl -S î- ergolinecorboxamide Cabergoline Reference s a GB 2 074 566 Farmitalia Carlo Erba . appl. GB-prior. . b US 4 526 892 Farmitalia .

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