TAILIEUCHUNG - BRAIN INJURY – PATHOGENESIS, MONITORING, RECOVERY AND MANAGEMENT

Why, then, have scores of drugs, previously found to be effective in animal models, failed clinical trials? The average clinician will answer this question by saying that animal experiments are useless, that they do not reflect the human situation, that they are badly designed and carried out, and so forth. Meetings and committees have even been celebrated to declare this truth, and to teach preclinical neuroscientists how to properly carry out their experiments, see for example the “STAIR” (Stroke Therapy Academic Industry Roundtable) meetings in the US | BRAIN INJURY -PATHOGENESIS MONITORING RECOVERY AND MANAGEMENT Edited by Amit Agrawal Brain Injury - Pathogenesis Monitoring Recovery and Management Edited by Amit Agrawal Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Bojan Rafaj Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published March 2012 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Brain Injury - Pathogenesis Monitoring Recovery and Management Edited by Amit Agrawal p. cm. ISBN 978-953-51-0265-6 INTECH open .

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