TAILIEUCHUNG - True status of smear-positive pulmonary tuberculosis defaulters in Malawi

This may be attributed to the fact that previous study was carried out in children. Previous report has shown that collection and processing of specimen for TB diagnosis in children is often problematic and prone to contamination especially in endemic settings with limited human and infrastructural facilities16. Also, recent trainings in Good Laboratory Practice by the laboratory scientists may account for their subsequent improvement in processing clinical specimens. Almost all (eight of the nine) positive AFB samples were from the age bracket 20-60 yr. This is worrisome as this age group constitutes the economic vibrant group of the population. TB infection affecting the vibrant work force may further aggravate shortage of HCWs which may. | Research True status of smear-positive pulmonary tuberculosis defaulters in Malawi . Kruyt 1 . Kruyt 2 . Boeree 3 . Harries 4 . Salaniponi 5 . van Noord6 The article reports the results of a study to determine the true outcome of 8 months of treatment received by smearpositive pulmonary tuberculosis PTB patients who had been registered as defaulters in the Queen Elizabeth Central Hospital QECH and Mlambe Mission Hospital MMH Blantyre Malawi. The treatment outcomes were documented from the tuberculosis registers of all patients registered between 1 October 1994 and 30 September 1995. The true treatment outcome for patients who had been registered as defaulters was determined by making personal inquiries at the treatment units and the residences of patients or relatives and in a few cases by writing to the appropriate postal address. Interviews were carried out with patients who had defaulted and were still alive and with matched fully compliant PTB patients who had successfully completed the treatment to determine the factors associated with defaulter status. Of the 1099 patients 126 had been registered as defaulters and the true treatment outcome was determined for 101 80 of the latter only 22 were true defaulters 31 had completed the treatment 31 had died during the treatment period and 17 had left the area. A total of 8 of the 22 true defaulters were still alive and were compared with the compliant patients. Two significant characteristics were associated with the defaulters they were unmarried and they did not know the correct duration of antituberculosis treatment. Many of the smear-positive tuberculosis patients who had been registered as defaulters in the Blantyre district were found to have different treatment outcomes without defaulting. The quality of reporting in the health facilities must therefore be improved in order to exclude individuals who are not true defaulters. Voir page 389 le résumé en franpais. En la página 390 figura .

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