TAILIEUCHUNG - báo cáo khoa học: "Sentinel lymph node biopsy for high-risk cutaneous squamous cell carcinoma: clinical experience and review of literature"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Sentinel lymph node biopsy for high-risk cutaneous squamous cell carcinoma: clinical experience and review of literature | Kwon et al. World Journal of Surgical Oncology 2011 9 80 http content 9 1 80 WORLD JOURNAL OF SURGICAL ONCOLOGY REVIEW Open Access Sentinel lymph node biopsy for high-risk cutaneous squamous cell carcinoma clinical experience and review of literature Steve Kwon1 Zhao Ming Dong2 and Peter C Wu1 3 Abstract High-risk cutaneous squamous cell carcinoma SCC is associated with an increased risk of metastases. The role of sentinel lymph node SLN biopsy in these patients remains unclear. To address this uncertainty we collected clinical data on six patients with clinical N0 high-risk SCC that underwent SLN biopsy between 1999 and 2006 and performed a literature review of SLN procedures for SCC to study the utility of SLN biopsy. There were no positive SLN identified among six cases and there was one local and one distant recurrence on follow-up. Literature review identified 130 reported cases of SLN biopsy for SCC. The SLN positivity rate was and false negative rate was 0 and and the negative predictive value was 100 and for all sites head neck and truncal extremity sites respectively. SLN biopsy remains an investigational staging tool in clinically node-negative high-risk SCC patients. The higher false negative rate and lower negative predictive value among SCC of the trunk extremity compared to SCC of the head neck sites suggests a more cautious approach when treating patients with the former. Given the paucity of long-term follow up an emphasis is placed upon the need for close surveillance regardless of SLN status. Keywords sentinel lymph node squamous cell carcinoma cutaneous staging Introduction Cutaneous squamous cell carcinoma SCC is overall the second most common skin cancer with approximately 200 000 new cases diagnosed each year in the . and accounts for nearly 25 of annual skin cancer deaths 1-4 . Fortunately the majority of cases is associated with a favorable prognosis and is often curable by surgical or local

TÀI LIỆU LIÊN QUAN
TAILIEUCHUNG - Chia sẻ tài liệu không giới hạn
Địa chỉ : 444 Hoang Hoa Tham, Hanoi, Viet Nam
Website : tailieuchung.com
Email : tailieuchung20@gmail.com
Tailieuchung.com là thư viện tài liệu trực tuyến, nơi chia sẽ trao đổi hàng triệu tài liệu như luận văn đồ án, sách, giáo trình, đề thi.
Chúng tôi không chịu trách nhiệm liên quan đến các vấn đề bản quyền nội dung tài liệu được thành viên tự nguyện đăng tải lên, nếu phát hiện thấy tài liệu xấu hoặc tài liệu có bản quyền xin hãy email cho chúng tôi.
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.