TAILIEUCHUNG - ALZHEIMER’S DISEASE PATHOGENESIS-CORE CONCEPTS, SHIFTING PARADIGMS AND THERAPEUTIC TARGETS

Central to the development of glomerular inflammation and injury are alterations and abnormalities of various cytokines and signaling systems. There are four chapters in this book that deal with these aspects in the pathogenesis. The role of TGF-β in progressive glomerular disease is discussed in great detail in a chapter well written by Hyun Soon Lee, with particular reference to mesangial matrix accumulation, while the role of STAT3 activation in glomerulonephritis is elaborated in the well written chapter by Fumio Tsuji et al. There are two chapters that review the role of two signaling pathways in glomerular disorders – rennin angiotensin system and the mammalian target of rapamycin. | ALZHEIMER S DISEASE PATHOGENESIS-CORE CONCEPTS SHIFTING PARADIGMS AND THERAPEUTIC TARGETS Edited by Suzanne De La Monte Alzheimer s Disease Pathogenesis-Core Concepts Shifting Paradigms and Therapeutic Targets Edited by Suzanne De La Monte Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2011 InTech All chapters are Open Access articles distributed under the Creative Commons Non Commercial Share Alike Attribution license which permits to copy distribute transmit and adapt the work in any medium so long as the original work is properly cited. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published articles. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Petra Zobic Technical Editor Teodora Smiljanic Cover Designer Jan Hyrat Image Copyright Carsten Erler 2010. Used under license from First published August 2011 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Alzheimer s Disease Pathogenesis-Core Concepts Shifting Paradigms and Therapeutic Targets Edited by Suzanne De La Monte p. cm. 978-953-307-690-4 ikrrr iJ OPEN ACCESS INI Cvn PUBLISHER INTECH open free online editions of InTech Books and Journals can be found at .

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