TAILIEUCHUNG - Báo cáo khoa hoc:" Another look at multiplicative models in quantitative genetics"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: Another look at multiplicative models in quantitative genetics | 543 Genet. Sei. Evol. 30 1998 543-564 Inra Elsevier Paris Original article Another look at multiplicative models in quantitative genetics Christine Dillmanna Jean-Louis Foulley1 a Station de génétique végétale INA-PG ferme de Moulon 91190 Gif-sur-Yvette France b Station de génétique quantitative et appliquée Institut national de la recherche agronomique 78352 Jouy-en-Josas cedex France Received 29 April 1998 accepted 22 September 1998 Abstract - This paper reviews basic theory and features of the multiplicative model of gene action. A formal decomposition of the mean and of the genotypic variance is presented. Connections between the statistical parameters of this model and those of the factorial decomposition into additive dominance and epistatic effects are also emphasized. General formulae for the genotypic covariance among inbred relatives are given in the case of linkage equilibrium. It is shown that neglecting the epistatic components of variation makes the multiplicative model a pseudo-additive one since this approximation does not break the strong dependency between mean and variance effects. Similarities and differences between the classical polygenic additivedominance and the multiplicative gene action approaches are outlined and discussed. Numerical examples for the biallelic case are produced to illustrate that comparison. Inra Elsevier Paris multiplicative gene action covariance among relatives inbreeding Resume - Un autre regard sur le modèle multiplicatif en génétique quantitative. Cet article présente la théorie et les principales caractéristiques du modèle multipli-catif d action des genes. Une decomposition formelie de la moyenne et de la variance génotypique permet d etablir les relations entre les paramètres statistiques de ce modèle et ceux issus de la decomposition factorielle de 1 effet des genes en effets addi-tifs de dominance et d epistasie. Une formule générale de la covariance entre appar-entés dans une population consanguine en .

• Báo cáo khoa học
• Báo cáo sinh học hay
• cách trình bày báo cáo
• báo cáo sinh học
• công trình nghiên cứu sinh học
• tài liệu về sinh học