TAILIEUCHUNG - Báo cáo sinh học: "Cytogenetic and molecular characterization of eight new reciprocal translocations in the pig species. Estimation of their incidence in French populations"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: Cytogenetic and molecular characterization of eight new reciprocal translocations in the pig species. Estimation of their incidence in French populations | 389 Genet. Sel. Evol. 34 2002 389-406 INRA EDP Sciences 2002 DOI gse 2002014 Original article Cytogenetic and molecular characterization of eight new reciprocal translocations in the pig species. Estimation of their incidence in French populations Alain DUCOSa Alain PINTONa Martine YERLEb Anne SÉGUÉLAa Hélène-Marie BERLANDa Corinne BRUN-BARONNATa Nathalie BONNETa Roland DARRÉa a UMRINRA-ENVT de cytogénétique des populations animales École nationale vétérinaire de Toulouse 23 Chemin des capelles 31076 Toulouse Cedex 3 France b Institut national de la recherche agronomique Laboratoire de génétique cellulaire Auzeville BP 27 31326 Castanet-Tolosan Cedex France Received 25 October 2001 accepted 20 December 2001 Abstract - Eight new cases of reciprocal translocation in the domestic pig are described. All the rearrangements were highlighted using GTG banding techniques. Chromosome painting experiments were also carried out to confirm the proposed hypotheses and to accurately locate the breakpoints. Three translocations rcp 4 6 q21 p14 rcp 2 6 p17 q27 andrcp 5 17 p12 q13 were found in boars siring small litters and piglets born alive per litter on average for translocations 2 6 and 5 17 respectively . The remaining five rcp 5 8 p12 q21 rcp 15 17 q24 q21 rcp 7 8 q24 p21 rcp 5 8 p11 p23 and rcp 3 15 q27 q13 were identified in young boars controlled before entering reproduction. A decrease in prolificacy of 22 was estimated for the 3 15 translocation after reproduction of the boar carrier. A parental origin by inheritance of the translocation was established for the 5 8 p11 p23 translocation. The overall incidence of reciprocal translocations in the French pig populations over the 2000 2001 period was estimated . chromosome reciprocal translocation pig reproductive performance chromosome painting Correspondence and reprints E-mail 390 A. Ducos et al. 1. INTRODUCTION Structural chromosomal abnormalities have long been studied in the pig .

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