TAILIEUCHUNG - ‘IN SILICO’ SIMULATION OF BIOLOGICAL PROCESSES

During the past two decades, reductionist biological science has generated new empirical data on the molecular foundations of biological structure and function at an accelerating rate. The list of organisms whose complete genomes have been sequenced is growing by the week. Annotations of these sequences are becoming more comprehensive, and databases of protein structure are growing at impressive, indeed formerly unimaginable rates. Molecular mechanisms for fundamental processes such as ligand^receptor interactions and signal transduction are being elucidated in exquisite structural detail | In Silico Simulation of Biological Processes Novartis Foundation Symposium Volume 247 Edited by Gregory Bock and Jamie A. Goode Copyright Novartis Foundation 2002. Simpo PDF Merge and Split Unregistered VersionS- http INSILICƠ SIMULATION OF BIOLOGICAL PROCESSES Simpo PDF Merge and Split Unregistered Version - http The Novartis Foundation is an international scientific and educational charity UK Registered Charity No. 313574 . Known until September 1997 as the Ciba Foundation it was established in 1947 by the CIBA company ofBasle which merged with Sandoz in 1996 to form Novartis. The Foundation operates independently in London under English trust law. It was formally opened on 22 June 1949. The Foundation promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research. To this end it organizes internationally acclaimed meetings typically eight symposia and allied open meetings and 15 20 discussion meetings each year and publishes eight books per year featuring the presented papers and discussions from the symposia. Although primarily an operational rather than a grant-making foundation it awards bursaries to young scientists to attend the symposia and afterwards work with one of the other participants. The Foundation s headquarters at 41 Portland Place London W1B 1BN provide library facilities open to graduates in science and allied disciplines. Media relations are fostered by regular press conferences and by articles prepared by the Foundation s Science Writer in Residence. The Foundation offers accommodation and meeting facilities to visiting scientists and their societies. Information on all Foundation activities can be found at http Simpo PDF Merge and Split Unregl redV sioryhttpV IN SILICO SIMULATION OF BIOLOGICAL PROCESSES 2002 JOHN WILEY SONS .

• Sinh học
• biological modelling
• phenomena in biology
• Model validation
• heoretical biology
• aboratory Bioinformatics
• Modelling the bacterial
• Scientific reports
• scientific research
• biochemistry
• breast cancer
• biological activities
• gastric cancer
• Modelling
• Virtual Crack Closure
• Technique and Finite
• Predicting the Delamination
• Growth Initiation
• Composite Structures
• BMC Chemistry
• Thiazole derivatives
• Antimicrobial activity
• Anticancer activity
• Molecular docking
• BMC Bioinformatics
• Bayesian networks
• Genetic regulatory networks
• Hierarchical bayesian modelling
• Biological interactions
• High throughput sequencing
• Powerful statistical models
• Meaningful biological signal
• Advantage illustrated
• Drosophila dataset
• Parameter estimation
• Global optimisation
• Parameter bounding
• Dynamic modelling