TAILIEUCHUNG - Background Paper of the Task Force on Child Health and Maternal Health

Invasive Meningococcal Disease results from bacterial infection with Neisseria meningitidis, a gram-negative aerobic organism that is usually a commensal in humans; 5-25% of adults are asymptomatic carriers. 8 Meningococci that cause invasive disease develop a capsule that protects the organism from host defence mechanisms. IMD may present with a clinical spectrum that ranges from acute meningitis, with neck stiffness, photophobia and a bulging fontanelle (all symptoms may not be present), to rapidly progressive meningococcal septicaemia with a non-blanching rash, reduced conscious level, shock and multiorgan failure. Less common manifestations of IMD include pneumonia, conjunctivitis, otitis media, epiglottitis, arthritis, and pericarditis. . | Millenniumproject Commissioned by the UN Secretary General and supported by the UN Development Group Background Paper of the Task Force on Child Health and Maternal Health April 18 2003 Lead authors Lynn Freedman Meg Wirth Ronald Waldman Mushtaque Chowdhury Allan Rosenfield Comments are welcome and should be directed to Lynn Freedman email lpf1@ Note to the reader The Background Paper provides a preliminary overview of existing knowledge and scopes out the questions addressed by this Task Force. The analysis conclusions and recommendations contained herein should be considered as very preliminary as they are likely to evolve as the Task Force works toward its final report at the end of 2004. Comments and suggestions are welcome. Please cite this paper as Background Paper of the Millennium Project Task Force on Child Health and Maternal Health. Disclaimer This publication does not necessarily reflect the views of the United Nations Development Programme UNDP its Executive Board or its Member States. Mailman School of Public Health Columbia University Bangladesh Rural Advancement Committee BRAC Acknowledgements The views expressed in this background document are those of the authors the coordination team for Task Force 4. We have benefited from comments on earlier drafts provided by some Task Force members particularly the Honorable Dr. Francisco Songane Minister of Health Mozambique Carla AbouZahr and colleagues from the World Health Organziation Jennifer Bryce and colleagues from the World Health Organization France Donnay of UNFPA Elizabeth Lule and colleagues from the World Bank Robert Black of Johns Hopkins School of Public Health Vinod Paul of All India Institute of Medical Sciences Angela Kamara of the RPMM Network and Adrienne Germain of International Women s Health Coalition. In addition the authors would like to extend their thanks to the following colleagues who generously reviewed and provided input on drafts of the background paper Deborah .

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