TAILIEUCHUNG - Chapter 068. Hematopoietic Stem Cells (Part 1)

Harrison's Internal Medicine Chapter 68. Hematopoietic Stem Cells Hematopoietic Stem Cells: Introduction All of the cell types in the peripheral blood and some cells in every tissue of the body are derived from hematopoietic (hemo: blood; poiesis: creation) stem cells. If the hematopoietic stem cell is damaged and can no longer function (., due to the nuclear accident at Chernobyl), a person would survive 2–4 weeks in the absence of extraordinary support measures. With the clinical use of hematopoietic stem cells, tens of thousands of lives are saved each year (Chap. 108). Stem cells produce tens of billions of. | Chapter 068. Hematopoietic Stem Cells Part 1 Harrison s Internal Medicine Chapter 68. Hematopoietic Stem Cells Hematopoietic Stem Cells Introduction All of the cell types in the peripheral blood and some cells in every tissue of the body are derived from hematopoietic hemo blood poiesis creation stem cells. If the hematopoietic stem cell is damaged and can no longer function . due to the nuclear accident at Chernobyl a person would survive 2-4 weeks in the absence of extraordinary support measures. With the clinical use of hematopoietic stem cells tens of thousands of lives are saved each year Chap. 108 . Stem cells produce tens of billions of blood cells daily from a stem cell pool that is estimated to be only in the hundreds of thousands. How stem cells do this how they persist for many decades despite the production demands and how they may be better used in clinical care are important issues in medicine. The study of blood cell production has become a paradigm for how other tissues may be organized and regulated. Basic research in hematopoiesis that includes defining stepwise molecular changes accompanying functional changes in maturing cells aggregating cells into functional subgroups and demonstrating hematopoietic stem cell regulation by a specialized microenvironment are concepts worked out in hematology but they offer models for other tissues. Moreover these concepts may not be restricted to normal tissue function but extend to malignancy. Stem cells are rare cells among a heterogeneous population of cell types and their behavior is assessed mainly in experimental animal models involving reconstitution of hematopoiesis. Thus much of what we know about stem cells is imprecise and based on inferences from genetically manipulated animals. Cardinal Functions of Hematopoietic Stem Cells All stem cell types have two cardinal functions self-renewal and differentiation Fig. 68-1 . Stem cells exist to generate maintain and repair tissues. They function .

• Y học thường thức
• Hematopoietic Stem Cells
• bệnh học và điều trị
• bài giảng bệnh học
• tài liệu y khoa
• harrison interal medicine
• BMC Pediatrics
• Very small embryonic like stem cells
• Peripheral blood circulating stem cells
• Blood testing
• Premature infants
• BMC Cancer
• Hematopoietic stem cell mobilization
• Peripheral blood stem cell transplantation
• Bone marrow
• Non Hodgkin’s lymphoma
• Conditioned medium
• Umbilical cord
• Umbilical cord blood
• Mesenchymal stem cells
• Hematopoietic stem cell
• Mesenchymal stem
• Stromal cells
• Progenitor cells capable
• Homogeneous progenitor cell
• Genome Biology
• Chromatin architecture
• Chromosome 11
• Nuclear envelope protein LaminA/C
• Spermatogonial stem cells
• Radiated mice
• Gamma ray
• Chemical and biological
• The science of stem cells
• Cell differentiation
• Stem cells in the body
• Wound healing and cancer
• Cell differentiation
• The hematopoietic system
• Mesenchymal stromal cells
• Sca 1+MSCs
• Hematopoietic microenvironment
• Antigen presentation ability
• Myelodysplastic syndromes
• Hematopoietic cells
• Acute myeloid leukemia
• Hematopoietic stem cell transplantation
• Graft versus host disease
• Wharton’s jelly
• Peripheral blood stem cells
• Insufficient graft
• Autologous stem cell transplantation
• Multiple myeloma
• immunogenetics
• neuron replacement therapy
• cover hematopoietic
• stem cells
• Cell Research
• Gene Therapy
• báo cáo khoa học
• báo cáo y học
• công trình nghiên cứu về y học
• tài liệu về y học
• cách trình bày báo cáo
• BMC Bioinformatics
• Functional gene set
• Dynamic network biomarker
• Relative effect analysis
• Leukemic stem cell
• AML outcome
• TRPM2 gene expression
• Abnormal myeloid progenitor cells
• BMC Anesthesiology
• Endothelial progenitor cells
• Hypoxia inducible factor 1α
• Stromal cell derived factor 1α
• báo cáo hóa học
• công trình nghiên cứu về hóa học
• tài liệu về hóa học
• Osteogenesis Imperfecta
• Laminopathies
• Progeria Syndrome
• Genetic Determinants
• Heart Rate Variation
• Cardiovascular Diseases