TAILIEUCHUNG - Chapter 068. Hematopoietic Stem Cells (Part 4)

Hierarchy of hematopoietic differentiation. Stem cells are multipotent cells that are the source of all descendant cells and have the capacity to provide either long-term (measured in years) or short-term (measured in months) cell production. Progenitor cells have a more limited spectrum of cells they can produce and are generally a short-lived, highly proliferative population also known as transient amplifying cells. Precursor cells are cells committed to a single blood cell lineage but with a continued ability to proliferate; they do not have all the features of a fully mature cell. Mature cells are the terminally differentiated product of. | Chapter 068. Hematopoietic Stem Cells Part 4 Hierarchy of hematopoietic differentiation. Stem cells are multipotent cells that are the source of all descendant cells and have the capacity to provide either long-term measured in years or short-term measured in months cell production. Progenitor cells have a more limited spectrum of cells they can produce and are generally a short-lived highly proliferative population also known as transient amplifying cells. Precursor cells are cells committed to a single blood cell lineage but with a continued ability to proliferate they do not have all the features of a fully mature cell. Mature cells are the terminally differentiated product of the differentiation process and are the effector cells of specific activities of the blood and immune system. Progress through the pathways is mediated by alterations in gene expression. The regulation of the differentiation by soluble factors and cell-cell communications within the bone marrow niche are still being defined. The transcription factors that characterize particular cell transitions are illustrated on the arrows the soluble factors that contribute to the differentiation process are in blue. SCF stem cell factor EPO erythropoietin TPO thrombopoietin. Figure 68-3 More Sour f ut A5 K p rOL nur ld Ej H vi r 51. Longo C L. ri iori llO J WtaTn rpjt r ftroc jltr of InfxnuJ 17th Edition http wvw. cccjjrri dii Cop nfl t Th 1 Hc jr -Hlll CornptnMfj Inc All rights rilt ixd. Relative function of cells in the hematopoietic hierarchy. The boxes represent distinct functional features of cells in the myeloid upper box versus lymphoid lower box lineages. Self-Renewal The hematopoietic stem cell must balance its three potential fates apoptosis self-renewal and differentiation. The proliferation of cells is generally not associated with the ability to undergo a self-renewing division except among memory T and B cells and among stem cells. Self-renewal capacity gives way to .

• Y học thường thức
• Hematopoietic Stem Cells
• bệnh học và điều trị
• bài giảng bệnh học
• tài liệu y khoa
• harrison interal medicine
• BMC Pediatrics
• Very small embryonic like stem cells
• Peripheral blood circulating stem cells
• Blood testing
• Premature infants
• BMC Cancer
• Hematopoietic stem cell mobilization
• Peripheral blood stem cell transplantation
• Bone marrow
• Non Hodgkin’s lymphoma
• Conditioned medium
• Umbilical cord
• Umbilical cord blood
• Mesenchymal stem cells
• Hematopoietic stem cell
• Mesenchymal stem
• Stromal cells
• Progenitor cells capable
• Homogeneous progenitor cell
• Genome Biology
• Chromatin architecture
• Chromosome 11
• Nuclear envelope protein LaminA/C
• Spermatogonial stem cells
• Radiated mice
• Gamma ray
• Chemical and biological
• The science of stem cells
• Cell differentiation
• Stem cells in the body
• Wound healing and cancer
• Cell differentiation
• The hematopoietic system
• Mesenchymal stromal cells
• Sca 1+MSCs
• Hematopoietic microenvironment
• Antigen presentation ability
• Myelodysplastic syndromes
• Hematopoietic cells
• Acute myeloid leukemia
• Hematopoietic stem cell transplantation
• Graft versus host disease
• Wharton’s jelly
• Peripheral blood stem cells
• Insufficient graft
• Autologous stem cell transplantation
• Multiple myeloma
• immunogenetics
• neuron replacement therapy
• cover hematopoietic
• stem cells
• Cell Research
• Gene Therapy
• báo cáo khoa học
• báo cáo y học
• công trình nghiên cứu về y học
• tài liệu về y học
• cách trình bày báo cáo
• BMC Bioinformatics
• Functional gene set
• Dynamic network biomarker
• Relative effect analysis
• Leukemic stem cell
• AML outcome
• TRPM2 gene expression
• Abnormal myeloid progenitor cells
• BMC Anesthesiology
• Endothelial progenitor cells
• Hypoxia inducible factor 1α
• Stromal cell derived factor 1α
• báo cáo hóa học
• công trình nghiên cứu về hóa học
• tài liệu về hóa học
• Osteogenesis Imperfecta
• Laminopathies
• Progeria Syndrome
• Genetic Determinants
• Heart Rate Variation
• Cardiovascular Diseases