TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 174

Pharmaceutical Substances Syntheses, Patents, Applications - Part 174. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Propiram P 1731 n COOH h2n ch3 2-phenoxybutyric 6-arninopenicillanic acid acid CI-CO-O-CH2-CH CH3 2 N C2H5 j isobutyl chloroformate triethylamine Reference s GB 877 120 Beecham appl. USA-prior. . GB 899 199 Pfizer appl. USA-prior. . GB 904 576 Bayer appl. D-prior. . GB 958 478 Beecham appl. USA-prior. . DE 1 143 817 Beecham appl. USA-prior. . DE 1 154 805 Bayer appl. . DE 1 159 449 Grünenthal appl. . Formulation s f. c. tabl. 280 mg 700 mg syrup 70 mg tabl. 125 mg 140 mg 280 mg 700 mg as potassium salt Trade Name s D Baycillin Bayer Vital Ultrapen Pfizer wfm Trescillin Beecham- Pluscillin Bayropharm 1 Bayercillin Bayer wfm Fujisawa F Brocilline Nativelie wfm J Oracillin Takeda GB Brocillin Beecham wfm Synthepen-P Meiji Propiram ATC- N02 Use analgesic RN 15686-91-6 MF C16H25N3O MW EINECS 239-775-7 LD50 290 mg kg M . 366 mg kg R . CN N- l-methyl-2- l-piperidinyl ethyl -V-2-pyridinylpropanamide fumarate 1 1 RN 13717-04-9 MF C16H25N3O C4H4O4 MW EINECS 237-270-6 LD50 mg kg M . 874 mg kg M . mg kg R . 1289 mg kg R . 1 g kg dog . NaNH2 sodium amide 2-amino pyridine 2-chloro-1 -piperidino-propane 2- 2-piperidino-1 -methylethylamino -pyridîne I 1732 P Propiverinc i hjc y V ch3 ----- 0 0 propionic onhydride Reference s US 3 163 654 Bayer D-prior. . FR 1 492 761 Bayer appl. D-prior. . combinations US 4 479 956 Analgesic Assoc. appl. . Trade Name s I Algeril Bayer wfm Propiverine atc G04BD06 zp4 Use anticholinergic treatment of incontinence RN 60569-19-9 MF C23H29NO3 MW . CN oc-Phcnyl-a-propoxybenzeneacetic acid 1 -methyl-4-piperidinyl ester hydrochloride RN 54556-98-8 MF C23H29NO3 HC1 MW diethyl oxolote ethyl benzilote I of. benactyzine synthesis 1-methyl-4-piperidinol H ni HO soci2 ------ IV Propofol P 1733 COOH .

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