TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 86

Pharmaceutical Substances Syntheses, Patents, Applications - Part 86. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Fenspiride F 851 2-amino-4-chloro- 5-sulfamoylbenzamide Reference s Biressi . et al. Farmaco Ed. Sei. FRPSAX 24 199 1969 . Formulation s cps. mg as potassium sait Trade Name s I Idrolone Maggioni- Winthrop Fenspiride ATC R03BX01 RO3DXO3 Use antiasthmatic bronchodilator a-adrenergic blocker RN 5053-06-5 MF C15H20N2O2 MW EINECS 225-751-3 LD50 230 mg kg M . CN 8- 2-phenylethyl -l-oxa-3 8-diazaspiro decan-2-one monohydrochloride RN 5053-08-7 MF C15H2 N2O2 HC1 MW EINECS 225-752-9 LDM 106 mg kg M . 250 mg kg M . 122 mg kg R . 437 mg kg R . 74 mg kg dog . 1 - 2-phenylethyl -4-piperldone KCN LiAIH4 lithium olanote 0 _ n _ H3C O 0 CH3 diethyl carbonate Reference s US 3 399 192 Science Union GB-prior. . preparation of l- 2-phenylethyl -4-piperidone Beckett et al. J. Med. Pharm. Chem. JMPCAS 1 37 51 1959 . Elpem et al. J. Am. Chem. Soc. JACSAT 80 4916 1958 . Dutta A K. Xu c Reith . J. Med. Chem. JMCMAR 39 3 749 1966 . Janssens F. et al. J. Med. Chem. JMCMAR 28 12 1925 1985 . 852 F Fentanyl Formulation s cps. 40 mg 80 mg suppos. 40 mg 80 mg Trade Name s F Pneumorel Euthérapie as I Espiran ICT hydrochloride Fenspir Ibirn Fluiden Lafare Pneumorel Stroder Fentanyl ATC N01AH01 N02AB03 Use analgesic narcotic RN 437-38-7 MF C22H21iN2O MW EINECS 207-113-6 LD5i 2900 pg kg M . 368 mg kg M . 2910 pg kg R . 18 mg kg R . CN A -phenyl-A -l 1 - 2-phenylethyl -4-piperidinyl propanamide citrate 1 1 RN 990-73-8 MF C22H2SN2O C6H8O7 MW EINECS 213-588-0 LD 0 10100 pg kg M . 368 mg kg M . 990 pg kg R . 18 mg kg R . 4-onilino-1 -benzylpiperidine I 1 -benzyl-4-piperidone aniline 0 0 propionic anhydride alanate N- 4-piperidyl -prapionanilide II 2-phenylethyl chloride Vn O Reference s FR 2 430 M Janssen appl. USA-prior. . US 3 141 823 Janssen appl. . US 3 164 600 Janssen appl. . Formulation s amp. mg 2 ml 10 ml as citrate .

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