TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 85

Pharmaceutical Substances Syntheses, Patents, Applications - Part 85. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Fenfluramine F 841 monohydrochloride RN 1892-80-4 MF C18H23N5O2 HC1 MW EINECS 217-580-8 LD50 55 mg kg M . 347 mg kg M . 100 mg kg R . CH3 7- 2 chloroethyl theophylline 1 -methyl-2-phenylethylamine theophylline phenylacetone Fenetylline Reference s DE 1 123 329 Degussa appl. addition to DE 1 095 285 appl. . US 3 029 239 Degussa D-prior. . Formulation s . f. c. tabl. 50 mg as hydrochloride Trade Name s D Captagon ASTA Medica F Captagon Gerda wfm AWD Captagon Promdeica wfm Fenfluramine atc A08AA02 Use appetite depressant anorexic RN 458-24-2 MF C12H16F3N MW EINECS 207-276-3 LD50 145 mg kg M . 130 mg kg R . 100 mg kg dog . CN A-ethyl-a-methyl-3- trifluoromethyl benzeneethanamine hydrochloride RN 404-82-0 MF C12H16F3N HC1 MW EINECS 206-968-2 LDS0 90 mg kg M . 170 mg kg M . 69 mg kg R . 23 mg kg dog . 100 mg kg dog . 842 F Fenipentol CFj 3-trifluoromethyl-phenyQacetone h2n-oh hydroxylomine 3-trïfluoromethyl-phenyl acetone H2 Raney Ni ------------- cf3 2-omino-1 - 3-trifluoromethyl- oxime phenyQprapone I OHC CH3 acetaldehyde H2 Raney-Ni ------------- Reference s FR-M 1 658 Science-Union appl. MC-prior. . Formulation s cps. 20 mg 60 mg s. r. cps. 60 mg tabl. 20 mg 40 mg as hydrochloride Trade Name s D Ponderax Boehringer F Ponderal Biopharma as Pesos Valeas Ing. wfm hydrochloride Ponderal Servier Ponderax Itherapia wfm GB I Ponderax Servier wfm Dimafen Stroder USA Pondimin Robins Fenipentol ATC A05AX Use choleretic RN 583-03-9 MF ChH16O MW EINECS 209-493-9 LD50 2900 mg kg M . 5432 mg kg R . CN a-butylbenzenemethanol CHO benzaldehyde butylmagnesium bromide Reference s GB 915 815 Thomae appl. valid from . US 3 084 100 Thomae appl. . Adams . Vander-Werf . J. Am. Chem. Soc. JACSAT 72 4368 1950 . Engelhorn R. . ARZNAD 10 255 1960 . Koss . et al. . ARZNAD 12 1026 1962 . .

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