TAILIEUCHUNG - Exercise-based dysphagia rehabilitation for adults with oesophageal cancer: A systematic review

Dysphagia is prevalent in oesophageal cancer with signifcant clinical and psychosocial complications. The purpose of this study was i) to examine the impact of exercise-based dysphagia rehabilitation on clinical and quality of life outcomes in this population and ii) to identify key rehabilitation components that may inform future research in this area. | Gillman et al. BMC Cancer 2022 22 53 https s12885-021-09155-y RESEARCH ARTICLE Open Access Exercise-based dysphagia rehabilitation for adults with oesophageal cancer a systematic review Anna Gillman1 Michelle Hayes2 Greg Sheaf3 Margaret Walshe1 John V. Reynolds4 and Julie Regan1 Abstract Background Dysphagia is prevalent in oesophageal cancer with significant clinical and psychosocial complications. The purpose of this study was i to examine the impact of exercise-based dysphagia rehabilitation on clinical and quality of life outcomes in this population and ii to identify key rehabilitation components that may inform future research in this area. Methods Randomised control trials RCT non-RCTs cohort studies and case series were included. 10 databases CINAHL Complete MEDLINE EMBASE Web of Science CENTRAL and ProQuest Dissertations and Theses Open- Grey PROSPERO RIAN and SpeechBITE 3 clinical trial registries and relevant conference abstracts were searched in November 2020. Two independent authors assessed articles for eligibility before completing data extraction qual- ity assessment using ROBINS-I and Downs and Black Checklist followed by descriptive data analysis. The primary outcomes included oral intake respiratory status and quality of life. All comparable outcomes were combined and discussed throughout the manuscript as primary and secondary outcomes. Results Three single centre non-randomised control studies involving 311 participants were included. A meta- analysis could not be completed due to study heterogeneity. SLT-led post-operative dysphagia intervention led to sig- nificantly earlier start to oral intake and reduced length of post-operative hospital stay. No studies found a reduction in aspiration pneumonia rates and no studies included patient reported or quality of life outcomes. Of the reported secondary outcomes swallow prehabilitation resulted in significantly improved swallow efficiency following oesoph- ageal surgery compared .

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• BMC Cancer
• Oesophageal cancer
• Curative treatment
• Dysphagia swallowing rehabilitation
• Swallow exercises
• Cancer patient pathways
• Colorectal cancer
• Lung cancer
• Breast cancer
• Prostate cancer
• Ovarian cancer
• Cancer detection
• Ovarian cancer symptoms
• Ovarian cancer signs
• Ovarian cancer tests
• Cancer biomarkers
• Pediatric cancer
• Familial cancer predisposition
• Hereditary cancer syndrome
• Genetic cancer susceptibility
• Advanced cancer
• Biliary tract cancer
• Multimodal intervention
• Pancreatic cancer
• Physical activity
• Breast cancer screening
• Familial breast cancer
• Young breast cancer survivors
• High risk relatives
• Randomized trial
• Childhood cancer
• Childhood cancer survivor
• Thyroid cancer screening
• Secondary cancer
• Cancer screening
• Community awareness
• Cancer education
• Cervical cancer
• Prior cancer
• Cancer survivors
• Cancer registry
• Second cancer
• Surgical oncology
• Cancer imaging
• Radiation oncologists
• Medical oncologists
• Oesophagogastric cancer
• Liver cancer
• Hepatobiliary cancer
• Multidisciplinary rehabilitation
• EGFR mutation
• Family history of cancer
• Inherited susceptibility
• Cancer predisposition genes
• Lung cancer aetiology
• Cancer stem cells
• Oct4 overexpressing lung cancer
• Human lung cancer xenograft model
• Disease free survivals
• Cancer hallmarks
• Cancer genesis
• Defiant disease
• Mutational signature
• Cancer diagnosis
• Cancer genomics
• Molecular medicine
• Whole genome sequencing
• Cancer susceptibility gene
• Breast cancer prognosis
• Next generation sequencing
• Quality of care
• Quality indicators
• Shifting cancer care
• German cancer society
• Colorectal cancer screening
• Stomach cancer screening
• Lung cancer survivor
• Physician recommendation
• Total number of lymph nodes
• Lymph node ratio
• Left colon cancer
• Right colon cancer
• Overall survival
• Cumulative incidence
• Esophageal cancer
• Head and neck cancer
• Metachronous cancer
• Young onset
• Reproductive cancer
• Risk factor
• Early detection of cancer
• Gastric cancer incidence
• Population based specialized registry
• Gastric cancer survival
• Gastric cancer clinical characteristics
• Gastric cancer pathological characteristics
• Lung Cancer Screening
• Racial disparities
• Lung Cancer diagnosis
• Screening adherence
• Second primary colorectal cancer
• Standardized incidence ratio
• Left sided colon cancer
• Right sided colon cancer
• Quality of cancer care
• Population based study