TAILIEUCHUNG - Noma in a boy with septic shock: A case report

Noma is a rare disease, which is characterized by rapid progression and a high rate of mortality; however, relatively few cases of noma infection accompanied by septic shock in children have been described. Further, most health care professionals have no knowledge of this disease or of its clinical significance. | Xu et al. BMC Pediatrics 2019 19 200 https s12887-019-1574-8 CASE REPORT Noma in a boy with septic shock a case report Open Access Check for updates Lili Xu . Wanrui Wei23 Xiaohua Ge3 Sibei Wan 1 3 Jing Yu1 and Xiaodong Zhu1 Abstract Background Noma is a rare disease which is characterized by rapid progression and a high rate of mortality however relatively few cases of noma infection accompanied by septic shock in children have been described. Further most health care professionals have no knowledge of this disease or of its clinical significance. Case presentation Herein we present a case report of a six-year-old male patient who was diagnosed with noma infection at a Chinese pediatric medical intensive care unit PMICU at which time it was discovered that he had septic shock. Following treatment by continuous renal replacement therapy CRRT for septic shock arising from noma the patient was in generally good condition and the local wound was seen to be essentially healed five weeks post-admission. Conclusion Noma is an opportunistic infectious disease condition. Treatment of the acute phase of noma predominantly focuses on controlling the infection and improving systemic conditions. In addition CRRT could be considered as a treatment option for cases that present with noma accompanied by septic shock. Keywords Noma Cancrum oris Septic shock Continuous renal replacement therapy Pediatrics Background Noma which is commonly known as cancrum oris is an acutely progressive and necrotic disease that is induced by infections and most commonly seen in malnourished and immuno-suppressed children 1 . Moreover if the patient is in septic shock the mortality rate can be as high as 50 or more 2 and if left untreated mortality may be up to 85 3 . There are few reports in the peer-reviewed literature of pediatric noma that is complicated by septic shock. Furthermore the treatment of noma in the acute phase of progression mainly serves to improve the general .

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