TAILIEUCHUNG - Changing trends in resistance pattern of Methicillin resistant staphylococcus aureus in burn patients

Historically, S. aureus has been one of the most common pathogens which caused pyogenic local and systemic infections in both hospitals and community. Methicillin resistance in Staphylococcus aureus is associated with multidrug resistance, an aggressive course, increased mortality and morbidity in both community and health care facilities. This cross sectional study was carried out in a 70 burn patients from May 2016 to July 2018 at , Nanded India. Swabs were taken and cultured for bacterial isolation and identification following standard operative procedures. Antimicrobial susceptibility was performed by Kirby Bauer’s disc diffusion method which used a 30µg Cefoxitin disc according to CLSI 2018 guidelines. MRSA isolates showed high resistance to ciprofloxacin (), gentamicin () as compared to other drugs. High prevalence of Ciprofloxacin resistance was detected. Multi resistant MRSA with a ‘D’ test positive was 79%. All MRSA isolates were sensitive to Vancomycin, Linezolid. MRSA had displayed increase in resistance to most antibiotics with ‘D’ test positive in recent years. Taking into consideration the prevalence of multidrug-resistance in MRSA, resistance patterns should be evaluated periodically and antibiotic therapy should be guided by susceptibility testing. | Changing trends in resistance pattern of Methicillin resistant staphylococcus aureus in burn patients

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• Methicillin resistant staphylococcus aureus
• Burn patients
• Resistance pattern
• Changing trends in resistance pattern
• Multidrug resistance
• Staphylococcus aureus
• Prevalence of Staphylococcus aureus
• Staphylococcus aureus from milk
• Milk products
• Virulent gene characterization
• Methicillin sensitive staphylococcus aureus
• Bovine mastitis
• Staphylococcal enterotoxin genes
• Antimicrobial sensitivity pattern
• Methicillin resistant coagulase negative
• Staphylococcus isolated
• Various clinical samples
• Antimicrobial resistance
• Antibiogram of methicillin resistant Staphylococcus aureus
• Tertiary care rural hospital
• Investigate their sensitivity pattern
• Epsilometer test
• Retail meat shops and customers
• Neonatal septicemia
• Incidence of methicillin resistant
• Tertiary Care Hospital
• Challenges in management
• Diabetic foot infections
• Diabetic foot Infection
• BMC Chemistry
• β Lactam affinity
• Healthcare associated MRSA
• Healthcare workers
• MRSA carriage
• Nasal carriage
• BMC Genomics
• Intercellular adhesion
• Biofilm production
• Antimicrobial therapy
• Coa gene
• Length polymorphism
• PCR restriction fragment
• Staphylococcus aureus based
• Molecular typing of methicillin resistant
• Methicillinresistant Staphylococcus aureus
• Polymerase chain reaction
• Bovine raw milk by PCR
• Inducible clindamycin resistance
• Double disc diffusion method
• Antibacterial activities
• Plant extracts
• Methicillin resistant
• Non microbial origin
• Community acquired methicillin resistant
• Soft tissue infections
• Both health care
• Community settings now
• Poultry meat
• Antibiotic Sensitivity
• MecA gene
• Poultry house environment
• Detection and molecular characterization
• Methicillin resistant staphylococcus aureus obtained
• Health careassociated infections
• Antimicrobial susceptibility testing
• Health care worker
• Different areas of cardiac
• MSSA and chromogenic media
• ICU patients
• Oxacillin susceptible mecA positive isolates
• Bacteriological profile
• Chronic suppurative otitis media
• Aerobic bacteriological profile
• Special reference
• Susceptibility pattern
• Rural Kerala
• Tertiary care hospital study
• Prompt infection control measures
• World health organization
• MRSA infections
• Antibiotic susceptibility pattern
• Particular communities
• Antimicrobial susceptibility pattern
• Around Trivandrum
• Nasal swab and blood
• Antimicrobial chemotherapy
• Antibiotic sensitivity pattern
• Methicillin resistant staphylococcus aureus isolated
• Various clinical specimen
• Tertiary care post graduate teaching institute