TAILIEUCHUNG - Evaluation of relationship between tests, clinical factors to change intracerebral hematoma volume in acute supratentorial hemorrhage

Increase in hematoma volume (HV) in the brain after intracerebral hemorrhage (ICH) is a major cause of worsening clinical condition, and is an independent predictor for mortality and outcome. Our goals were to evaluate the relationship between subclinical, clinical factors to change intracerebral HV in acute supratentorial hemorrhage in first 72 hours after onset. | Journal of military pharmaco-medicine 7-2013 EVALUATION OF RELATIONSHIP BETWEEN TESTS, CLINICAL FACTORS TO CHANGE INTRACEREBRAL Hematoma Volume IN ACUTE SUPRATENTORIAL HEMORRHAGE Dinh Vinh Quang*; Nguyen Van Chuong** summary Increase in hematoma volume (HV) in the brain after intracerebral hemorrhage (ICH) is a major cause of worsening clinical condition, and is an independent predictor for mortality and outcome. Our goals were to evaluate the relationship between subclinical, clinical factors to change intracerebral HV in acute supratentorial hemorrhage in first 72 hours after onset. Descriptive, prospective analysis of 188 acute supratentorial hemorrhage patients associated with hypertension at admission, admitted within six hours after onset, from 2010 to 2013. Results: The average age was , including 128 males (68%) and 60 females (32%). Univariate analysis showed that 9 important factors related to increased HV were: (1) Glasgow on admission, (2) NIHSS on admission, (3) Rankin at admission, (4) SBP at admission, (5) Hematoma volume, (6) Shape of hematoma, (7) Spot sign, (8) WBC, and (9) Glycemie. Multivariate analysis showed that two independent prognostic factors associated with increasing HV were: (1) The shape of the hematoma is irregular on CT, and (2) Spot sign on CTA. * Key words: Acute supratentorial hemorrhage; Subclinical, clinical factors. INTRODUCTION Stroke, one of the causes of death in neurological diseases, or prolonged sequelae and disabilities, is a common disorder. Intracerebral hemorrhage (ICH) accounted for 15 to 20% of stroke, causing death or severe disability more than cerebral infarction [3]. In ICH appeared, risk factors, hypertension and cerebral amyloid angiopathy accounted for 78-88% [2]. When ICH appears, there are some factors affecting to clinical status of the patient (PT). An increase in HV in the brain after ICH is a major cause worsening clinical condition and is an independent predictor for mortality and outcome .

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