TAILIEUCHUNG - Chemical constituents from ethyl acetate extract of scoparia dulcis linn.
This research focuses on the isolation and characterization of eight natural compounds from the ethyl acetate extract of Scoparia dulcis L. collected in An Giang province, Vietnam. Six flavonoid compounds: apigenin (1), luteolin (2), baicalein (3), oroxylin A (4), oroxylin A 7-O-βD-glucoside (5) and vitexin (6) along with two nitrogen-containing compounds: 2,4-dihydroxy1,4-benzoxazin-3-one (7) and uracil (8) were successfully isolated via the methods of natural product extraction. | Journal of Science and Technology 54 (2C) (2016) 278-283 CHEMICAL CONSTITUENTS FROM ETHYL ACETATE EXTRACT OF SCOPARIA DULCIS LINN. Ton Nu Lien Huong *, Le Thi Diem Trinh, Van Nguyen Anh Duy, Le Thanh Cong, Nguyen Tan Qui, Nguyen Duy Thanh Department of Chemistry, College of Natural Science, Can Tho University, Campus 2, 3/2 Street, Ninh Kieu, Can Tho City, Vietnam * Email: tnlhuong@ Received: 30 May 2016; Accepted for publication: 23 October 2016 ABSTRACT This research focuses on the isolation and characterization of eight natural compounds from the ethyl acetate extract of Scoparia dulcis L. collected in An Giang province, Vietnam. Six flavonoid compounds: apigenin (1), luteolin (2), baicalein (3), oroxylin A (4), oroxylin A 7-O-βD-glucoside (5) and vitexin (6) along with two nitrogen-containing compounds: 2,4-dihydroxy1,4-benzoxazin-3-one (7) and uracil (8) were successfully isolated via the methods of natural product extraction. The structures of these compounds were elucidated base on 1D-NMR and 2D-NMR spectral data as well as MS and compared with those in the authentic reports. This study contributed new results to the phytochemical examination of Scoparia dulcis Linn. growing in Vietnam with the presence of the first isolated compounds as (3), (4), (5), (7) and (8). Keywords: Scoparia dulcis Linn., ethyl acetate extract, apigenin, luteolin, baicalein, oroxylin A, vitexin, oroxylin A 7-O-β-D-glucoside, DIBOA, uracil. 1. INTRODUCTION The medicinal plant Scoparia dulcis L., commonly known as sweet broomweed or goatweed, is a species belonging to the Scrophulariaceae family. It is an edible herb mainly found in many tropical regions around the world such as Mexico, India, Thailand, Malaysia, etc. In Vietnam, Scoparia dulcis is naturally distributed from north to south; due to the valuable medicinal properties of this herb so that it has been cultivated throughout the country. Traditionally, all parts of the plant are used to treat various diseases. .
đang nạp các trang xem trước
