TAILIEUCHUNG - Systems for Research and Evaluation for Translating GenomE-Based discoveries for health

How variations in genes contribute to variations in disease risk has been a subject of study for more than 100 years (IOM, 2006). Until fairly recently research focused on single genes that give rise to rare genetic diseases such as cystic fibrosis or Huntington’s disease. With the advent of genome-wide association (GWA) studies, however, numerous associations between specific gene loci and complex diseases have been identified, for example for breast cancer, type II diabetes, coronary artery disease, asthma, and bipolar disorder (Goldstein, 2009; Hardy and Singleton, 2009; Smith and Lusis, 2009) | INSTITUTE OF MEDICINE SYSTEMS FOR RESEARCH AND EVALUATION FOR TRANSLATING GENOME-BASED DISCOVERIES FOR HEALTH SYSTEMS FOR RESEARCH AND EVALUATION FOR TRANSLATING GENOME-BASED DISCOVERIES FOR HEALTH WORKSHOP SUMMARY Theresa Wizemann Rapporteur Roundtable on Translating Genomic-Based Research for Health Board on Health Sciences Policy INSTITUTE OF MEDICINE OF THE NATIONAL ACADEMIES THE NATIONAL ACADEMIES PRESS Washington . THE NATIONAL ACADEMIES PRESS 500 Fifth Street . Washington DC 20001 NOTICE The project that is the subject of this report was approved by the Governing Board of the National Research Council whose members are drawn from the councils of the National Academy of Sciences the National Academy of Engineering and the Institute of Medicine. This project was supported by contracts between the National Academy of Sciences and American College of Medical Genetics unnumbered contract American College of Physicians unnumbered contract American Medical Association unnumbered contract American Nurses Association unnumbered contract AstraZeneca Pharmaceuticals Inc. unnumbered contract BlueCross BlueShield Association unnumbered contract Centers for Disease Control and Prevention CDC Contract No. 200-2005-13434 College of American Pathologists unnumbered contract Department of Veterans Affairs VA Contract No. V101 93 P-2238 Eli Lilly and Company Contract No. LRL-0028-07 Genetic Alliance unnumbered contract Genomic Health Inc. unnumbered contract Human Resources and Services Administration Johnson Johnson unnumbered contract Kaiser Permanente unnumbered contract National Cancer Institute Contract No. N01-OD-4-2139 TO 189 National Heart Lung and Blood Institute Contract No. N01-OD-4-2139 TO 189 National Human Genome Research Institute Contract No. N01-OD-4-2139 TO 189 National Institute of Child Health and Human Development Contract No. N01-OD-4-2139 TO 189 National Society of Genetic Counselors unnumbered contract Pfizer Inc. Contract No. .

• Tiếng Anh thương mại
• Veterans Health
• Health Administration
• Rare Disease
• translational process
• Data Sources
• Based discoveries
• BMC Women's Health
• Intervention development
• Provider perspectives
• Women veterans
• Veterans Health Administration
• Community health nursing
• leadership and management in nursing
• Men’s health
• Geriatric health
• Veterans’ health
• Management in nursing
• FINDINGS TO DATE
• Ascertainment Bias
• IOM Recommendations
• Nuclear Weapons
• Veterans Affairs
• HEALTH CARE
• báo cáo khoa học
• báo cáo y học
• công trình nghiên cứu về y học
• tài liệu về y học
• cách trình bày báo cáo
• Psychological Factors
• Conditioning Health
• Related Quality
• Elderly Women
• Urinary Incontinence
• Long Term Care
• báo cáo hóa học
• công trình nghiên cứu về hóa học
• tài liệu về hóa học
• statements and documents scientific reports
• medical reports
• medical knowledge
• medical research
• medical management
• BMC Cancer
• Non small cell lung Cancer
• Concurrent and sequential Chemoradiation
• Concurrent chemoradiation therapy
• Endometriosis
• Role of Ultrasound
• MRI and Other Imaging
• Modalities in Diagnosis
• Planning Intervention
• Pelvic Endometriosis
• clinical trials
• trình bày báo cáo
• tài liệu báo cáo khoa học
• kiến thức y học
• nghiên cứu y học
• Abdominopelvic Complications
• Complications of Endometriosis
• Diagnostics and Treatment
• Pathological Aspects
• Aspects of Endometriosis
• Barriers to care
• Military personnel
• Mental health
• Post traumatic stress disorder
• Common mental disorders
• Alcohol misuse
• Gray or White
• Language Deficits
• Novel Imaging
• Medical Therapy
• Current Status
• Future Targets