TAILIEUCHUNG - Neuromuscular Junction Disorders Diagnosis and Treatment

Diseases of the neuromuscular junction (NMJ) include a large spectrum of acquired and inherited disorders mainly characterized by fluctuating muscle weakness and fatigability of ocular, bulbar or limb muscles. Remarkable progress has been made in our understanding of the pathogenesis of these disorders in recent years. Furthermore, our ability to diagnose these conditions has improved significantly due to the widespread availability of immunologic tests, the use of in vitro electrophysiologic and microstructural studies, and the refinement of sensitive clinical electrodiagnostic tests of neuromuscular transmission. Despite these advances, significant questions remain to be answered by the researcher and the clinician, and disagreement exists amongst specialists regarding therapy and management of patients. This. | Neuromuscular Junction Disorders Diagnosis and Treatment Matthew N. Meriggioli James F. Howard Jr. c. Michel Harper Neuromuscular Junction Disorders Diagnosis and Treatment Matthew N. Meriggioli Rush-Presbyterian-St. Luke s Medical Center Chicago Illinois . James E Howard Jr. University of North Carolina at Chapel Hill Chapel Hill North Carolina . c. Michel Harper Mayo Clinic Foundation Rochester Minnesota . MARCEL DEKKER Marcel Dekker Inc. New York Basel Although great care has been taken to provide accurate and current information neither the author s nor the publisher nor anyone else associated with this publication shall be liable for any loss damage or liability directly or indirectly caused or alleged to be caused by this book. The material contained herein is not intended to provide specific advice or recommendations for any specific situation. Trademark notice Product or corporate names may be trademarks or registered trademarks and are used only for identification and explanation without intent to infringe. Library of Congress Cataloging-in-Publication Data A catalog record for this book is available from the Library of Congress. ISBN 0-8247-4079-3 This book is printed on acid-free paper. Headquarters Marcel Dekker Inc. 270 Madison Avenue New York NY 10016 . tel 212-696-9000 fax 212-685-4540 Distribution and Customer Service Marcel Dekker Inc. Cimarron Road Monticello New York 12701 . tel 800-228-1160 fax 845-796-1772 Eastern Hemisphere Distribution Marcel Dekker AG Hutgasse 4 Postfach 812 CH-4001 Basel Switzerland tel 41-61-260-6300 fax 41-61-260-6333 World Wide Web http The publisher offers discounts on this book when ordered in bulk quantities. For more information write to Special Sales Professional Marketing at the headquarters address above. Copyright 2004 by Marcel Dekker Inc. All Rights Reserved. Neither this book nor any part may be reproduced or transmitted in any form or by any means electronic or .

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• Neuromuscular Junction
• Neuromuscular Transmission
• Presynaptic Disorders
• Neuromuscular Transmission
• Postsynaptic Disorders
• Manual of neurologic therapeutics
• Neurologic therapeutics
• Peripheral neuropathies
• Neuromuscular junction disorders
• Motor neuropathies
• Other demyelinating diseases
• BMC Musculoskeletal Disorders
• Muscle force
• Eccentric injury
• Collagen organization