TAILIEUCHUNG - Guidelines for Testing and Treatment of Latent Tuberculosis Infection

Despite the dramatic decline in the number of reported cases of tuberculosis (TB) in New York City, many New Yorkers remain at high risk for developing active tuberculosis disease, once infected with Mycobacterium tuberculosis. Groups at especially high risk include contacts of persons with active tuberculosis, HIV-infected persons, individuals with certain predisposing medical conditions, and recent immigrants from countries with high rates of TB. In April 2000, the American Thoracic Society (ATS) and the Centers for Disease Control and Prevention (CDC) revised their guidelines for the treatment of latent tuberculosis infection (LTBI). The Infectious Diseases Society of America and the American College of Physicians endorsed these guidelines. Sections. | Guidelines for Testing and Treatment of Latent Tuberculosis Infection Sonal Munsiff MD Diana Nilsen MD Felicia Dworkin MD NYC Department of Health Mental Hygiene Bureau of Tuberculosis Control TB IS PREVENTABLE Table of Contents Introduction October 2005 Page .2 Ten Points for Testing and Treatment of Latent Tuberculosis 1. Target all tuberculin skin testing to persons at high risk for 2. Test all people who are at high risk regardless of BCG 3. Decide which test to use for diagnosing latent TB 4. Determine if the test for TB infection is 5. Rule out active TB disease in persons with positive skin 6. Provide treatment for high-risk individuals diagnosed with latent TB infection regardless of 7. Take special care when testing and treating HIV-positive 8. Carefully consider treatment for pregnant women children contacts of persons with multidrug-resistant TB and individuals with evidence of old healed 9. Monitor all patients carefully during the treatment of 10. Ensure adherence during LTBI A Five-Step Guide to Tuberculin Skin Testing and Treatment of Latent Tuberculosis 1. Know whom to 2. Determine if the test is 3. Evaluate for TB 4. Give treatment for latent TB 5. Adjust treatment in HIV-positive patients taking antiretroviral Resources for Patient 1 Introduction Despite the dramatic decline in the number of reported cases of tuberculosis TB in New York City many New Yorkers remain at high risk for developing active tuberculosis disease once infected with Mycobacterium tuberculosis. Groups at especially high risk include contacts of persons with active tuberculosis HIV-infected persons individuals with certain predisposing medical conditions and recent immigrants from countries with high rates of TB. In April 2000 the American Thoracic Society ATS and the Centers for .

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