TAILIEUCHUNG - Detection of Pulmonary tuberculosis: comparing MR imaging with HRCT

Computer Tomography (CT) is considered the gold standard for assessing the morphological changes of lung parenchyma. Although novel CT techniques have substantially decreased the radiation dose, radiation exposure is still high. Magnetic Resonance Imaging (MRI) has been established as a radiation- free alternative to CT for several lung diseases, but its role in infectious diseases still needs to be explored further. Therefore, the purpose of our study was to compare MRI with high resolution CT (HRCT) for assessing pulmonary tuberculosis. Methods: 50 patients with culture-proven pulmonary tuberculosis underwent chest HRCT as the standard of reference and were evaluated by MRI within 24 h after HRCT. Altogether we. | Busi Rizzi et al. BMC Infectious Diseases 2011 11 243 http 1471-2334 11 243 BMC Infectious Diseases RESEARCH ARTICLE Open Access Detection of Pulmonary tuberculosis comparing MR imaging with HRCT 1 1 12 3 3 Elisa Busi Rizzi Vincenzo Schinina Massimo Cristofaro Delia Goletti Fabrizio Palmieri Nazario Bevilacqua Francesco N Lauria3 Enrico Girardi4 and Corrado Bibbolino1 Abstract Background Computer Tomography CT is considered the gold standard for assessing the morphological changes of lung parenchyma. Although novel CT techniques have substantially decreased the radiation dose radiation exposure is still high. Magnetic Resonance Imaging MRI has been established as a radiation- free alternative to CT for several lung diseases but its role in infectious diseases still needs to be explored further. Therefore the purpose of our study was to compare MRI with high resolution CT HRCT for assessing pulmonary tuberculosis. Methods 50 patients with culture-proven pulmonary tuberculosis underwent chest HRCT as the standard of reference and were evaluated by MRI within 24 h after HRCT. Altogether we performed 60 CT and MRI examinations because 10 patients were also examined by CT and MRI at follow- up. Pulmonary abnormalities their characteristics location and distribution were analyzed by two readers who were blinded to the HRCT results. Results Artifacts did not interfere with the diagnostic value of MRI. Both HRCT and MRI correctly diagnosed pulmonary tuberculosis and identified pulmonary abnormalities in all patients. There were no significant differences between the two techniques in terms of identifying the location and distribution of the lung lesions though the higher resolution of MRI did allow for better identification of parenchymal dishomogeneity caseosis and pleural or nodal involvement. Conclusion Technical developments and the refinement of pulse sequences have improved the quality and speed of MRI. Our data indicate that in terms of .

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