TAILIEUCHUNG - THE PHILIPPINE CLINICAL PRACTICE GUIDELINES ON THE DIAGNOSIS, TREATMENT AND CONTROL OF PULMONARY TUBERCULOSIS

The purpose of these guidelines is to provide the practicing physician with a rational and manageable approach to the diagnosis, treatment and control of pulmonary tuberculosis in the Philippines. By their very nature, these guidelines cannot encompass all eventualities. Care has been taken to confirm the accuracy of the information presented and to describe generally accepted practices. However, the authors, editors and publishers disclaim any and all liability for errors or omissions or for any consequences from application of the information in this text and make no warranty, expressed or implied, with respect to the contents of this publication. Under no circumstances will this text supervene the. | Clinical Practice Guideline Number 3 Diagnosis Treatment and Control of Tuberculosis THE PHILIPPINE CLINICAL PRACTICE GUIDELINES ON THE DIAGNOSIS TREATMENT AND CONTROL OF PULMONARY TUBERCULOSIS Report of the Task Force on Tuberculosis 2000 This guideline is intended for use by a broad range of healthcare professionals including medical specialists clinical practitioners administrators policy workers and nurses. Citation as to source is suggested in the following format Task Force on Tuberculosis Philippine Practice Guidelines Group in Infectious Diseases. Pulmonary Tuberculosis Clinical Practice Guidelines. PPGG-ID Philippine Society for Microbiology and Infectious Diseases and Philippine College of Chest Physicians. Philippine Practice Guidelines Group in Infectious Disease An Initiative of the Philippine Society for Microbiology and Infectious Disease and the Philippine College of Chest Physicians. Clinical Practice Guidelines PHILIPPINE COPYRIGHT 2000 By PPGG-ID Philippine Society for Microbiology and Infectious Diseases and Philippine College of Chest Physicians All Rights Reserved. TABLE OF CONTENTS Preamble iii Background xx Rationale iii Objectives iv Methods employed iv Introduction Tuberculosis problem in the Philippines 1 Rationale for the creation of TB consensus statements 1999 1 Diagnosis of pulmonary tuberculosis Clinical diagnosis 4 Laboratory diagnosis 7 Radiologic diagnosis 22 Treatment of tuberculosis Drug treatment of choice for newly-diagnosed PTB in the Philippines 36 Difference between 2 and 3 drugs in the maintenance phase of short-course treatment for PTB 42 MDR vs. non-MDR TB 42 Primary initial drug resistance and secondary drug resistance 42 Rate of MDR-TB in the Philippines 43 Correlation between bacteriologic drug resistance seen in-vitro with treatment response of patients 45 Interpreting the results of drug sensitivity testing for Mycobacteria 46 Risk of treatment failure for MDR-TB vs. non-MDR TB 47 Difference in treatment response .

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