TAILIEUCHUNG - The Health Effects of Fine Particulate Air Pollution: Lines that Connect

A study of physician office visits in London showed associations between air pollution and doctor visits for asthma and other lower respiratory disease. For children, levels of nitrogen dioxide, carbon monoxide, and sulfur dioxide were associated with increased numbers of medical consultations. However, in adults, the only consistent association was with levels of airborne particles. This suggests that children and adults might respond differently to pollution exposures. Prenatal Effects of Carbon Monoxide Carbon monoxide may also have prenatal effects. Pregnant women who were exposed to high levels of ambient carbon monoxide (5 ppm to 6. | CRITICAL REVIEW DISCUSSION ISSN 1047-3289 J. Air Waste Manage. Assoc. 56 1368-1380 Copyright 2006 Air Waste Management Association Health Effects of Fine Particulate Air Pollution Lines that Connect Judith C. Chow and John G. Watson Desert Research Institute Reno NV Joe L. Mauderly Lovelace Respiratory Research Institute Albuquerque NM Daniel L. Costa . Environmental Protection Agency Office of Research and Development Research Triangle Park NC Ronald E. Wyzga Electric Power Research Institute Palo Alto CA Sverre Vedal University of Washington Seattle WA George M. Hidy Envair Aerochem Placitas NM Sam L. Altshuler Consultant San Francisco CA David Marrack Fort Bend Medical Clinic Houston TX Jon M. Heuss Air Improvement Resource Inc. Novi MI George T. Wolff General Motors Public Policy Center Detroit MI C. Arden Pope III Brigham Young University Provo UT Douglas W. Dockery Harvard School of Public Health Boston MA INTRODUCTION Herein is the discussion of the 2006 A WMA Critical Review1 2 on Health Effects of Fine Particulate Air Pollution Lines that Connect. In the review Drs. C. Arden Pope III and Douglas Dockery addressed the epidemiological evidence for the effects of particulate matter PM on human health indicators. The review documents substantial progress since the 1997 Critical Review3 in the areas of 1 short-term exposure and mortality 2 long-term exposure and mortality 3 time scales of exposure 4 the shape of the concentration-response function 5 cardiovascular disease and 6 biological plausibility. Invited and contributing discussants agree and disagree with points made in the review. Each discussion is self-contained and adds information relevant to the topic. Joint authorship of this article does not imply that a discussant subscribes to the opinions expressed by others. Commentaries are the opinions of the author only and do not necessarily reflect the positions of their respective organizations. In particular Dr. Costa s comments have not been .

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