TAILIEUCHUNG - Antibiotic de-escalation

Everyone seems to agree that antibiotic de-escalation therapy seems to make sense. The big question is therefore why aren’t we doing it? Antibiotic de-escalation therapy is the practice of using more powerful antibiotics, earlier in treatment, for a short period of time – and then switching to a less powerful antibiotic once the infection is accurately diagnosed and under control. One could argue that the concept of “hit hard – hit fast” is not new. So why is this the case? I think that part of the conundrum is the disease process itself, which frequently is one of escalation | Antibiotic de-escalation Everyone seems to agree that antibiotic de-escalation therapy seems to make sense. The big question is therefore why aren t we doing it Antibiotic de-escalation therapy is the practice of using more powerful antibiotics earlier in treatment for a short period of time - and then switching to a less powerful antibiotic once the infection is accurately diagnosed and under control. One could argue that the concept of hit hard - hit fast is not new. So why is this the case I think that part of the conundrum is the disease process itself which frequently is one of escalation. A patient presenting on a ward in hospital may not initially have a serious infection. They may be admitted for something quite different like a broken limb and have no infection at all. But within a matter of days this situation can change and in particular for the more elderly complicated patients with underlying diseases co-morbidities the situation can deteriorate very rapidly. .de-escalation makes good sense and should be practiced. For example It would seem unnecessary foolish even to commence therapy for a mild chest infection with a very powerful antibiotic when the clinical signs and symptoms do not warrant this. But in some patients what appears to be a mild infection can progress to a more serious clinical situation. Diagnostic techniques in microbiology have still not advanced to the stage where early detection of a causative pathogen can be easily made. It remains the case that a 48 hour period will lapse before microbiological results can be obtained. So what happens then The results may reveal not one but several bacteria are present. This then becomes a sort of bacterial whodunit Are we witnessing a genuine polymicrobial infection or are some of those bacteria simply colonizing and not infecting the patient Which one is the real culprit and how should we target therapy to deal with it In some cases the microbiological results reveal. .nothing So the situation

• Y học thường thức
• chuyên ngành y khoa
• tài liệu y khoa
• lý thuyết y học
• giáo án y học
• bài giảng y học
• trắc nghiệm y học
• bài tập nghành y
• đề thi thử chuyên ngành y
• tài liệu y học
• nghiên cứu y khoa
• chuyên khoa tai mũi họng
• trắc nghiệm y khoa
• y học dân tộc
• y học phổ thông
• chuyên ngành y học
• kiến thức y học
• bài giảng y khoa
• chuẩn đoán bệnh y khoa
• tài liệu ngành y
• giáo trình ngành y
• chuyên khoa ngành Y
• viên tai xương chùm
• khó thở
• cấp cứu hồi sức
• Danh mục luận văn
• Luận văn chuyên ngành Thú y
• Chuyên ngành Khoa học Thú y
• Khoa học Thú y
• Ngành Thú y
• giáo trình y học
• bệnh lâm sàng
• chuẩn đoán bệnh
• y học cổ truyền
• y học thực hành
• bệnh thường gặp
• nghiên cứu y học