TAILIEUCHUNG - Báo cáo sinh học: " Genetic variation in the pleiotropic association between physical activity and body weight in mice"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Genetic variation in the pleiotropic association between physical activity and body weight in mice | Genetics Selection Evolution BioMed Central Open Access Genetic variation in the pleiotropic association between physical activity and body weight in mice Larry J Leamy 1 Daniel Pomp2 3 4 5 and J Timothy Lightfoot6 Address Department of Biology University of North Carolina at Charlotte Charlotte North Carolina 28223 USA 2Department of Genetics University of North Carolina Chapel Hill NC 27599 USA 3Department of Nutrition University of North Carolina Chapel Hill NC 27599 USA 4Department of Cell and Molecular Physiology University of North Carolina Chapel Hill NC 27599 USA 5Carolina Center for Genome Science University of North Carolina Chapel Hill NC 27599 USA and 6Department of Kinesiology University of North Carolina at Charlotte Charlotte North Carolina 28223 USA Email Larry J Leamy - ljleamy@ Daniel Pomp - dpomp@ J Timothy Lightfoot - jtlightf@ Corresponding author Published 23 September 2009 Received 23 March 2009 - . Accepted 23 September 2009 Genetics Selection Evolution 2009 41 41 doi 1297-9686-41-41 This article is available from http content 41 1 41 2009 Leamy et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background A sedentary lifestyle is often assumed to lead to increases in body weight and potentially obesity and related diseases but in fact little is known about the genetic association between physical activity and body weight. We tested for such an association between body weight and the distance duration and speed voluntarily run by 310 mice from the F2 generation produced from an intercross of two inbred lines that differed dramatically in their physical .

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